Shigellosis (bacillary dysentery) is an acute infectious disease mainly of the large bowel of humans and higher apes. Its characteristic symptoms are abdominal pain and diarrhea, which often contains blood, mucus, and pus. The causative agents of this disease are bacteria of the genus Shigella, which is divided into four subgroups or species: subgroup A (S. dysenteriae), subgroup B (S. flexneri), subgroup C (S. boydii), and subgroup D (S. sonnei). All of these organisms cause bacillary dysentery. It is known that certain strains of Escherichia coli (enteroinvasive E. coli) cause a disease clinically indistinguishable from bacillary dysentery.


Shiga Toxin Malnourished Child Shigella Flexneri Shigella Dysenteriae Shigella Sonnei 
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Literature Cited

  1. Black, R. E., G. F. Graun, and P. A. Blake. 1978. Epidemiology of common source outbreaks of shigellosis in the United States, 1961–1975. Am. J. Epidemiol. 108:47–52.PubMedGoogle Scholar
  2. Boileau, C. R., H. M. d’Haureville, and P. J. Sansonnetti. 1984. DNA hybridization technique to detect Shigella species and enteroinvasive Escherichia coli. J. Clin. Microbiol. 20:959–961.PubMedGoogle Scholar
  3. Dale, D. C., and L. T. Mata. 1968. Studies of diarrhea disease in Central America. XI. Intestinal bacterial flora in malnourished children with shigellosis. Am. J. Trop. Med. 17:397–403.Google Scholar
  4. DuPont, H. L., R. B. Hornick, M. J. Snyder, J. P. Libonati, S. B. Formal, and E. J. Gangarosa. 1972. Immunity in shigellosis. II. Protection induced by oral live vaccine or primary injection. J. Infect. Dis. 125:12–16.PubMedGoogle Scholar
  5. Ewing, W. H. 1986. Identification of Enterobacteriaceae, 4th ed. Elsevier Science Publishing, Inc., New York.Google Scholar
  6. Frost, J. A., B. Rowe, J. Vandepitte, and E. J. Threlfall. 1981. Plasmid characterization in investigation of an epidemic caused by multiple resistant Shigella dysenteriae type 1 in central Africa. Lancet 2:1074–1075.PubMedCrossRefGoogle Scholar
  7. Gross, R. J., L. V. Thomas, and B. Rowe, 1979. Shigella dysenteriae, S. flexneri and S. boydii infections in England and Wales: the importance of foreign travel. Br. Med. J. 280:744–750.Google Scholar
  8. Hale, T. L., and S. B. Formal. 1981. Protein synthesis in HeLa or Henle 407 cells infected with Shigella dysenteriae, Shigella flexneri 2a or Salmonella typhimurium W118. Infect. Immun. 32:137–144.PubMedGoogle Scholar
  9. Hollister, A. C., Jr., M. D. Beck, A. M. Gittelsohn, and E. C. Hemphill. 1955. Influence of water availability on Shigella prevalence in children of farm labor families. Am. J. Public Health 45:354–362.CrossRefGoogle Scholar
  10. Iseki, S., and Hamano, S. 1959. Conversion of type antigen IV in Shigella flexneri by bacteriophage. Proc. Jpn. Acad. Sci. 35:407–408.Google Scholar
  11. Keusch, G. T., and M. Jacewicz. 1977. The pathogenesis of Shigella diarrhea. VI. Toxin and antitoxin in Shigella flexneri and Shigella sonnei infections in humans. J. Infect. Dis. 135:552–556.Google Scholar
  12. Kopecko, D. J., O. Washington, and S. B. Formal. 1980. Genetic and physical evidence for plasmid control of Shigella sonnei form I surface antigen. Infect. Immun. 29:207–214.PubMedGoogle Scholar
  13. Koster, F., J. Levin, L. Walker, K. S. K. Tung, R. H. Gilman, M. M. Rahaman, M. A. Majid, S. Islam, and R. C. Williams. 1978. Haemolytic-uremic syndrome after shigellosis. N. Engl. J. Med. 298:927–933.PubMedCrossRefGoogle Scholar
  14. Kuhns, D. M., and T. G. Anderson. 1944. A fly-borne bacillary dysentery epidemic in a large military organization. Am. J. Public Health 34:750–754.CrossRefGoogle Scholar
  15. Macaden, R., B. N. Gokul, P. Pereira, and P. Bhat. 1980. Bacillary dysentery due to multidrug resistant Shigella dysenteriae 1. Indian J. Med. Res. 71:178–185.PubMedGoogle Scholar
  16. Mata, L. J., E. J. Gangarosa, A. Caceres, D. R. Perera, and M. L. Mejicanos. 1969. Epidemic Shiga bacillus in Central America. 1. Etiologic investigations in Guatemala. J. Infect. Dis. 122:170–180.CrossRefGoogle Scholar
  17. Mosley, W. H., B. Adams, and E. D. Lyman. 1962. Epidemiologic and sociologic features of a large urban outbreak of shigellosis. J. Am. Med. Assoc. 182:1307–1312.Google Scholar
  18. Murray, B. E. 1986. Resistance of Shigella, Salmonella and other selected enteric pathogens to antimicrobial agents. Rev. Infect. Dis. 8:S172–S181.PubMedCrossRefGoogle Scholar
  19. O’Brien, A. D., G. D. LaVeck, M. R. Thompson, and S. B. Formal. 1982. Production of Shigella dysenteriae type 1- like cytotoxin by Escherichia coli. J. Infect. Dis. 146:763–769.PubMedCrossRefGoogle Scholar
  20. Olsnes, S., and K. Eiklid. 1980. Isolation and characterization of Shigella Shiga cytotoxin. J. Biol. Chem. 255:284–289.PubMedGoogle Scholar
  21. Pál, T., A. S. Pácsa, L. Emödy, S. Vörös, and E. Sélley. 1985. Modified enzyme-linked immunosorbent assay for detecting enteroinvasive Escherichia coli and virulent Shigella strains. J. Clin. Microbiol. 21:415–418.PubMedGoogle Scholar
  22. Rahaman, M. M., M. M. Khan, K. M. S. Aziz, M. S. Islam, and A. K. M. G. Kibriya. 1975. An outbreak of dysentery caused by Shigella dysenteriae type 1 on a coral island in the Bay of Bengal. J. Infect. Dis. 132:15–19.PubMedCrossRefGoogle Scholar
  23. Sansonetti, P. J., T. L. Hale, G. J. Dammin, C. Kapfer, H. H. Collins, Jr., and S. B. Formal. 1983. Alterations in the pathogenicity of Escherichia coli K-12 after transfer of plasmid and chromosomal genes from Shigella flexneri. Infect. Immun. 39:1392–1402.PubMedGoogle Scholar
  24. Sansonetti, P. J., D. J. Kopecko, and S. B. Formal. 1981. Shigella sonnei plasmids: evidence that a large plasmid is necessary for virulence. Infect. Immun. 34:75–83.PubMedGoogle Scholar
  25. Sansonetti, P. J., D. J. Kopecko, and S. B. Formal. 1982. Involvement of a plasmid in the invasive ability of Shigella flexneri. Infect. Immun. 35:852–860.PubMedGoogle Scholar
  26. Serény, B. 1957. Experimental keratoconjunctivitis shigellosa. Acta Microbiol. Acad. Sci. Hung. 4:367–376.PubMedGoogle Scholar
  27. Thomas, M. E. M., and H. E. Tillett. 1973. Dysentery in general practice: a study of cases and their contacts in Enfield and an epidemiological comparison with salmonellosis. J. Hyg. 71:373–389.CrossRefGoogle Scholar
  28. Watanabe, H., and A. Nakamura. 1985. Large plasmids associated with virulence in Shigella species have a common function necessary for epithelial cell penetration. Infect. Immun. 48:391–396.Google Scholar
  29. Watanabe, H., and K. N. Timmis. 1984. A small plasmid in Shigella dysenteriae 1 specifies one or more functions essential for O-antigen production and bacterial virulence. Infect. Immun. 43:391–396.PubMedGoogle Scholar
  30. Watanabe, T. 1963. Infective heredity of multiple drug resistance in bacteria. Bacteriol. Rev. 27:87–115.PubMedGoogle Scholar

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© Springer-Verlag New York Inc. 1988

Authors and Affiliations

  • Haruo Watanabe

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