Abstract
Modern surgical antisepsis is now more than 120 years old. After Louis Pasteur’s discovery that bacteria caused fermentation, Joseph Lister recognized that bacteria also caused putrifaction in wounds. He utilized this information in 1865, in the treatment of a patient with an open tibial fracture, to which he applied lint dipped in liquid carbolic acid (38). His concept of chemical sterilization of the wound before bacteria could multiply sufficiently provided the groundwork for our modern era of surgical antisepsis.
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Goodman, S.B., Schurman, D.J. (1988). Prophylaxis in Orthopedic Surgery. In: Schlossberg, D. (eds) Orthopedic Infection. Clinical Topics in Infectious Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3870-6_11
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DOI: https://doi.org/10.1007/978-1-4612-3870-6_11
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