Intraspinal SEPs Recorded from the Vicinity of the Dorsal Root Entry Zone

  • J. A. Campbell
  • J. B. Miles
Conference paper


Intraspinal recordings of somatosensory evoked potentials have been performed at this centre for several years in patients undergoing radio-frequency percutaneous cervical cordotomy for the relief of malignant pain (Campbell and Lipton, 1983, 1984,1985; Campbell and Bowsher, 1985; Campbell, 1985). These recordings have been used both as a research tool in the investigation of sensory transmission in the human spinal cord and as an extra aid for accurate positioning of the lesion electrode within the spinal cord. Some open neurosurgical procedures also require accurate localization of spinal tracts and it was felt that similar techniques may prove valuable in these cases. As a result, responses evoked by peripheral nerve stimulation have been recorded from various positions within the spinal cord during ablative neurosurgical procedures. Somatosensory evoked potentials have been recorded from the cords of 6 patients undergoing destruction of the dorsal root entry zone (DREZ), 2 patients having a midline myelotomy and 1 patient on whom an open thoracic cordotomy was performed.


Peroneal Nerve Dorsal Column Peripheral Nerve Stimulation Human Spinal Cord Dorsal Root Entry Zone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Brodal, A.: Neurological Anatomy in Relation to Clinical Medicine. Oxford Univ. Press, N.Y., 1981Google Scholar
  2. 2.
    Campbell, J.A.: Observations on somatosensory evoked potentials recorded from within the human spinal cord. Ph.D. Thesis, University of Liverpool, 1985Google Scholar
  3. 3.
    Campbell, J.A. and Bowsher, D.: Electrical activity recorded from within the anterolateral funiculus during percutaneous cordotomy in man. Phil. Trans. Roy. Soc. London, B, 1985, 308, 422CrossRefGoogle Scholar
  4. 4.
    Campbell, J.A. and Lipton, S.: Somatosensory evoked potentials recorded from within the anterolateral quadrant of the human spinal cord, In: J.J. Bonica et al. (Eds.). Advances in Pain Research and Therapy, Vol. 5,1983, pp. 193–196Google Scholar
  5. 5.
    Campbell, J.A. and Lipton, S.: Intraspinal evoked potentials in man during cervical cordotomy, In: S. Homma and T. Tamaki (Eds.). Fundamentals and Clinical Application of Spinal Cord Monitoring, Saikon Pub. Co. Tokyo, 1984, pp. 245–252Google Scholar
  6. 6.
    Campbell, J.A. and Lipton, S.: Intraspinal evoked potentials in man, In: C. Morocutti and P.A. Rizzo (Eds.). Evoked Potentials. Neurophysiological and Clinical Aspects, Elsevier Science Publishers B.V., 37–43, 1985Google Scholar
  7. 7.
    Jones, S.J. and Thomas, D.G.: Assessment of long sensory tract conduction in patients undergoing dorsal root entry zone coagulation for pain relief, In: J. Schramm and S.J. Jones (Eds.). Spinal Cord Monitoring, Springer Verlag, Berlin, 1985Google Scholar

Copyright information

© Springer-Verlag New York Inc. 1998

Authors and Affiliations

  • J. A. Campbell
    • 1
  • J. B. Miles
  1. 1.Pain Relief FoundationLiverpoolUK

Personalised recommendations