Mice Immunized to Insulin Develop Anti-idiotypic Antibody to the Insulin Receptor

  • Yoram Shechter
  • Dana Elias
  • Rafael Bruck
  • Ruth Maron
  • Irun R. Cohen


Several diseases of man can be related to the formation of autoantibodies that interact with surface receptors. Examples are the antibodies that trigger TSH receptor in Graves’ disease (1), antibodies that bind to and block the receptor for acetylcholine at the neuromuscular junction in myasthenia gravis (2), and antibodies that trigger insulin like responses which appear in certain (very rare) types of severe insulin-resistant diabetes (3).


Insulin Receptor Receptor Antibody Bovine Insulin Insulin Antibody Booster Injection 
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Copyright information

© Springer-Verlag New York Inc. 1988

Authors and Affiliations

  • Yoram Shechter
  • Dana Elias
  • Rafael Bruck
  • Ruth Maron
  • Irun R. Cohen

There are no affiliations available

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