A New Uniform Grading System (Using Mayo Clinic Material)

Abstract

Brain tumors are subdivided into groups defined by their histology. This is true regardless of the viewpoint from which they are studied: surgical, clinical pathologic, radiologic or in fundamental research. However, if the histologic groups are heterogeneous and not reproducible, a bias is introduced that will dramatically impair the validity of any result determined by any of these disciplines. This should make one conscious of the role and responsibilities of the pathologist in the field of brain tumors.