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Steroid Response Elements. Definition of a Minimal Promoter and Interaction with Other Activating Sequences

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Gene Regulation by Steroid Hormones IV

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Abstract

Control of gene expression by steroid hormones is exerted mainly by modulation of the transcriptional activity of the regulated genes. The response to the various steroid hormones is highly specific. It is mediated by binding of the hormone to its specific receptor which, after binding, attains the capacity to recognize a specific DNA region on regulated genes. This receptor-DNA interaction eventually leads in a still-unknown way to an increase of the rate of transcription of the target gene (Yamamoto, 1985).

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Author information

Authors and Affiliations

  1. Institute of Cell and Tumor Biology, German Cancer Research Center, Heidelberg, Germany

    W. Schmid, U. Strahle, R. Mestril, G. Klock, W. Ankenbauer & G. Schutz

Authors
  1. W. Schmid
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  2. U. Strahle
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  3. R. Mestril
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  4. G. Klock
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  5. W. Ankenbauer
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  6. G. Schutz
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Editor information

Editors and Affiliations

  1. Division of Molecular Genetics, Department of Obstetrics and Gynecology, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, Texas, 78284, USA

    Arun K. Roy

  2. Department of Cell Biology, Baylor College of Medicine, Houston, Texas, 77030, USA

    James H. Clark

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© 1989 Springer-Verlag New York, Inc.

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Schmid, W., Strahle, U., Mestril, R., Klock, G., Ankenbauer, W., Schutz, G. (1989). Steroid Response Elements. Definition of a Minimal Promoter and Interaction with Other Activating Sequences. In: Roy, A.K., Clark, J.H. (eds) Gene Regulation by Steroid Hormones IV. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3666-5_5

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  • DOI: https://doi.org/10.1007/978-1-4612-3666-5_5

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8197-9

  • Online ISBN: 978-1-4612-3666-5

  • eBook Packages: Springer Book Archive

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