Current Experience from the Interaction of Bacteria with Glycosphingolipids

  • Karl-Anders Karlsson
Conference paper

Abstract

The association of microbes to host animal cell surfaces is in most instances a specific recognition an interaction between a protein on the microbe (adhesin) and a protein or a carbohydrate on the animal cell. This has repeatedly been demonstrated for viruses (1–3), bacteria (3–5), bacterial toxins (3, 6) and parasites (3, 7). As far as known today the majority of attachment sites or receptors on host cells is made up of carbohydrates. One reason for this may be the abundance of various surface glycoconjugates, strictly membrane-bound as glycolipids, glycoproteins and proteoglycans, or more loosely associated as secreted glycoproteins and proteoglycans.

Keywords

Sugar Carbohydrate Carboxyl Diarrhea Microbe 

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Copyright information

© Springer-Verlag New York Inc. 1989

Authors and Affiliations

  • Karl-Anders Karlsson
    • 1
  1. 1.Department of Medical BiochemistryUniversity of GöteborgGöteborgSweden

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