Abstract
In the Ninth Workshop, the DR4 sera revealed some heterogeneity, and it appeared that some of the patterns correlated with B alleles and/or DW splits (1). There was also some difficulty distinguishing well characterized lymphoblastoid cell lines (LCLs) which would have been very useful, but few were available at the time. Furthermore, many laboratories experienced difficulty with DR and DQ typing on LCLs largely because of extra reactions.
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References
Williamson J, Tait B, Richiardi P, et al. Antigen report: HLA-DR4. In: Albert ED, Baur MP, Mayr WR (eds): Histocompatibility Testing 1984. Springer-Verlag, Berlin, 1984:188–189.
Grimsley G, Homes P, Townsend D, Williamson J, Dawkins RL. HLA typing of lymphoblastoid cell lines (LCL). In: Aizawa M (ed): HLA in Asia-Oceania 1986. Sapporo, Japan: Hokkaido University Press, 1986:909–913.
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Williamson, J. et al. (1989). Antigen Society #23 Report (DR4, DR9): Part 2: Serologic Typing of B-Lymphoblastoid Cell Lines: DR4 and DR9. In: Dupont, B. (eds) Immunobiology of HLA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3552-1_46
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DOI: https://doi.org/10.1007/978-1-4612-3552-1_46
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