• Allen R. Ronald


Chancroid is a sexually transmitted infection, clinically manifested by acute ulcers on the external genitalia and inguinal lymphadenopathy with bubo formation. Although it was initially described by Ricord in 1838, it was first differentiated from syphilis by Bassereau in 1852. Ducrey described the etiologic agent in 1889, but its cultivation on solid media was difficult and unpredictable. As a result, controversy about Haemophilus ducreyi and its role in chancroid continued until recently. Newer technologies that facilitate the culture of H. ducreyi now permit a specific diagnosis.


Herpes Simplex Genital Herpes Neisseria Gonorrhoeae Genital Ulcer Penile Shaft 
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  1. 1.
    Salzman RS, Kraus SJ, Miller RG, et al: Chancroidal ulcers that are not chancroid: Cause and epidemiology. Arch Dermatol 120:636–639, 1984.PubMedCrossRefGoogle Scholar
  2. 2.
    Sturm AW, Zanen HC: Characteristics of Haemophilus ducreyi in culture. J Clin Microbiol 19:672–674, 1984.PubMedGoogle Scholar
  3. 3.
    Dylewski J, Nsanze H, Maitha G, et al: A laboratory diagnosis of Haemophilus ducreyi: Sensitivity of culture media. Diag Microbiol Infect Dis 4:241–245, 1986.CrossRefGoogle Scholar
  4. 4.
    McNicol PJ, Ronald AR: The plasmids of Haemophilus ducreyi. J Antimicrob Chemother 14:561–573, 1984.PubMedCrossRefGoogle Scholar
  5. 5.
    Hammond GW, Slutchuk M, Scatliff J, et al: Epidemiologic, clinical, laboratory and therapeutic features of an urban outbreak of chancroid in North America. Rev Infect Dis 2:867–879, 1980.PubMedCrossRefGoogle Scholar
  6. 6.
    Blackmore CA, Limpakarnjanarat K, Rigau-Perez JG, et al: An outbreak of chancroid in Orange County, California: Descriptive epidemiology and disease-control measures. J Infect Dis 151:840–844, 1985.PubMedCrossRefGoogle Scholar
  7. 7.
    Kinghorn GR, Hafiz S, McEntegart MG: Pathogenic microbial flora of genital ulcers in Sheffield with particular reference to herpes simplex and Haemophilus ducreyi. Br J Vener Dis 58:377–380, 1982.PubMedGoogle Scholar
  8. 8.
    Plummer FA, D’Costa LJ, Nsanze H, et al: Clinical and microbiologic studies of genital ulcers in Kenyan women. Sex Trans Dis 12:193–197, 1985.CrossRefGoogle Scholar
  9. 9.
    Plummer FA, D’Costa LJ, Nsanze H, et al: Epidemiology of chancroid and Haemophilus ducreyi in Nairobi. Lancet 2:1293–1295, 1983.PubMedCrossRefGoogle Scholar
  10. 10.
    Chapel TA, Brown WJ, Jeffries C, et al: How reliable is the morphological diagnosis of penile ulcerations? Sex Trans Dis 4:150–152, 1977.CrossRefGoogle Scholar
  11. 11.
    Cameron DW, Plummer FA, Simonsen JN, et al: Female to male heterosexual transmission of HIV infection in Nairobi. 3rd International Conference on AIDS, Washington, D.C., 1987.Google Scholar
  12. 12.
    Kraus S J, Werman BS, Biddle JW, et al: Pseudogranuloma inguinale caused by Haemophilus ducreyi. Arch Dermatol 118:494–497, 1982.PubMedCrossRefGoogle Scholar
  13. 13.
    Hanschell HM: Sulphanilamide in the treatment of chancroid. Lancet 1:886–888, 1938.CrossRefGoogle Scholar
  14. 14.
    Tay1er DN, Pitarangsi C, Echeverria P, et al: Comparative study of ceftriaxone and trimethoprim-sulfamethoxazole for the treatment of chancroid in Thailand. J Infect Dis 152:1002–1006, 1986.CrossRefGoogle Scholar
  15. 15.
    Bowmer MI, Nsanze H, D’Costa LJ, et al: Single dose ceftriaxone for chancroid. Antimicrob Agents Chemother 21:67-69, 1987.Google Scholar
  16. 16.
    Ndinya-Achola JO, Nsanze H, Karasira P, et al: Three day oral course: Augmentin in the treatment of chancroid. Genitourin Med 62:202–204, 1986.PubMedGoogle Scholar
  17. 17.
    Naamara W, Plummer FA, Greenblatt R, et al: Treatment of chancroid with ciprofloxacin: A prospective randomized clinical trial. Am J Med 82(Suppl. 4A):317–320, 1987.PubMedGoogle Scholar

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© Springer-Verlag New York Inc. 1989

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  • Allen R. Ronald

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