X-Linkage Studies in Affective Disorders
Bipolar affective illness is a major and relatively common psychiatric condition characterized by recurrent manic and depressive episodes and variable age at onset. It has long been recognized that heredity plays an important role in the etiology of bipolar illness. This notion originated in studies of familial aggregation and was reinforced by twin and adoption data that favored a substantial genetic component in the transmission of the disorder. Yet the mode of genetic transmission and the specific genes involved remain unknown.
KeywordsBlindness Harness Mandel
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