Patient Characteristics and Factors Associated with Chronic Depression and Its Treatment
Depression in most patients remits spontaneously or responds to antidepressant treatment. The few patients in whom it does not form a group who pose a significant therapeutic challenge. Robins and Guze1 reviewed 20 follow-up studies of affective disorders and concluded that a chronic course supervened in 1–28% of cases (average 12–15%). This wide variation depends on nonuniformity of diagnostic criteria for depression, assessment methods employed, and in particular the intensity of follow-up. In this study the definition used was that of Cassano et al.2: “Chronicity refers to symptomatic nonrecovery for a period of 2 or more years and may be a sequel to one or more episodes of depression from which the patient does not recover.”
KeywordsBeck Depression Inventory Depressive Illness Chronic Depression Chronic Group Research Diagnostic Criterion
Unable to display preview. Download preview PDF.
- 1.Robins E, Guze S. Classification of affective disorders—the primary-secondary, the endogenous-reactive and the neurotic-psychotic dichotomies. In Williams TA, Katz MM, Shield JA (eds): Recent Advances in Psychobiology of the Depressive Illnesses. Washington, DC: US Government Printing Office, 1972.Google Scholar
- 3.Loudon JB, Eccleston D. Unpublished observations, 1976.Google Scholar
- 9.Paykel ES. Recent life events in the development of depressive disorders. In Depue RA (ed): The Psychobiology of the Depressive Disorders—Implications for the Effects of Stress. New York: Academic Press, 1979.Google Scholar
- 11.Eysenck HJ, Eysenck SBG. Manual of the Eysenck Personality Questionnaire. London: Hodder & Stoughton, 1975.Google Scholar