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Role of Endogenous Corticotropin-Releasing Factor in Modulating the Pituitary Response to Stress

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Neuropeptides and Stress

Part of the book series: Hans Selye Symposia on Neuroendocrinology and Stress ((HANS SELYE SYMP))

Abstract

The exposure of rats to stressful stimuli results in increased adrenocorticotropic hormone (ACTH) secretion with decreased luteinizing hormone (LH) and growth hormone (GH) release. Since corticotropin-releasing factor (CRF) is also released during stress1, we investigated the possibility that changes in its endogenous levels might mediate the effect of stress on pituitary function.

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References

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Authors
  1. Catherine Rivier
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  2. Felice Petraglia
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  3. Claire-Dominique Walker
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  4. Wylie Vale
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Editor information

Editors and Affiliations

  1. Department of Medicine, Los Angeles School of Medicine, University of California, Los Angeles, California, 90073, USA

    Yvette Taché Ph.D. (Professor and Member) (Professor and Member)

  2. Brain Research Institute, Los Angeles, California, 90024, USA

    Yvette Taché Ph.D. (Professor and Member) & John E. Morley M.D. (Director, Professor and Member) (Professor and Member) &  (Director, Professor and Member)

  3. Geriatric Research, Education, and Clinical Center, Sepulveda Veterans Administration Medical Center, Sepulveda, California, 91343, USA

    John E. Morley M.D. (Director, Professor and Member) (Director, Professor and Member)

  4. Department of Medicine, Los Angeles, School of Medicine, University of California, Los Angeles, California, 90024, USA

    John E. Morley M.D. (Director, Professor and Member) (Director, Professor and Member)

  5. Autonomic Physiology Laboratory, Departments of Medicine and Surgery, San Diego Medical Center, University of California, San Diego, California, 92103, USA

    Marvin R. Brown M.D. (Professor) (Professor)

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© 1989 Springer-Verlag New York Inc.

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Rivier, C., Petraglia, F., Walker, CD., Vale, W. (1989). Role of Endogenous Corticotropin-Releasing Factor in Modulating the Pituitary Response to Stress. In: Taché, Y., Morley, J.E., Brown, M.R. (eds) Neuropeptides and Stress. Hans Selye Symposia on Neuroendocrinology and Stress. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3514-9_2

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  • DOI: https://doi.org/10.1007/978-1-4612-3514-9_2

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-8135-1

  • Online ISBN: 978-1-4612-3514-9

  • eBook Packages: Springer Book Archive

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