Immunology of Entamoeba histolytica in Human and Experimental Hosts

  • V. K. Vinayak
Conference paper
Part of the Progress in Vaccinology book series (VACCINOLOGY, volume 2)

Abstract

Amebiasis, an invasive enteric protozoal infection that can spread to multiple organ systems, is a major public health problem. It is caused by the cytolytic parasite Entamoeba histolytica. It has a worldwide distribution, one estimate indicating that 480 million people carry the parasite in their intestinal tracts. Serological investigations suggest that in approximately one-tenth of the total infected population, i.e., approximately 48 million annually, the parasite has invaded the intestinal mucosa or liver (122). The great interest of the parasitologists, microbiologists, immunologists, pathologists, clinicians, and biochemists has resulted in a voluminous literature. Despite such interest, the complicated host-parasite relation, immunological responses, and effective immunoprophylaxis have not yet been elucidated.

Keywords

Cholesterol Corticosteroid Fractionation Immobilization Polypeptide 

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