Skip to main content
SpringerLink
Log in

Rationale for the Development of a Rotavirus Vaccine for Infants and Young Children

  • Conference paper
Progress in Vaccinology

Part of the book series: Progress in Vaccinology ((VACCINOLOGY,volume 2))

Abstract

Vaccinology is a relatively new term, but its very existence reflects the progress in vaccine development. The field of vaccinology embraces the breadth of biology ranging from molecular biologic initiatives to conven-tional, well-established techniques.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Albert MJ, Unicomb LE, Bishop RF: Cultivation and characterization of human rotaviruses with “supershort” RNA patterns. J Clin Microbiol 1987; 25: 1635–1640.

    PubMed  CAS  Google Scholar 

  2. Anderson EL, Belshe RB, Bartram J, et al: Evaluation of rhesus rota¬virus vaccine (MMU 18006) in infants and young children. J Infect Dis 1986; 153: 823–831.

    PubMed  CAS  Google Scholar 

  3. Ashley CR, Caul EO, Clark SKR, et al: Rotavirus infections of apes. Lancet 1979; 2: 477.

    Google Scholar 

  4. Bachmann P, Bishop RF, Flewett TH, et al: Nomenclature of human rota-viruses: designation of subgroups and serotypes. Bull WHO 1984;62:501– 503

    Google Scholar 

  5. Berglund ME, McAdaragh JP, Stotz I: Proceedings of the 26th Western Poultry disease conference at University of California, Davis, 1986, pp 129–130.

    Google Scholar 

  6. Bishop RF, Barnes GL, Cipriani E, Lund JS: Clinical immunity after neonatal rotavirus infection: a prospective longitudinal study in young children. N Engl J Med 1983; 309: 72–76.

    PubMed  CAS  Google Scholar 

  7. Bishop RF, Davidson GP, Holmes IH, Ruck BJ: Virus particles in epithelial cells of duodenal mucosa from children with viral gastroenteritis.Lancet 1973; 2: 1281–1283.

    PubMed  CAS  Google Scholar 

  8. Bishop RF, Davidson GP, Holmes IH, Ruck BJ: Detection of a new virus by electron microscopy of fecal extracts from children with acute gastroen¬teritis. Lancet 1974; 1: 149–151.

    PubMed  CAS  Google Scholar 

  9. Black RE, Greenberg HB, Kapikian AZ, et al: Acquisition of serum antibody to Norwalk virus and rotavirus and relation to diarrhea in a longitudinal study of young children in rural Bangladesh. J Infect Dis 1982; 145: 483–489.

    PubMed  CAS  Google Scholar 

  10. Black RE, Merson MH, Mizanur Rahman ASM, et al: A two-year study of bacterial, viral and parasitic agents associated with diarrhea in rural Ban-gladesh. J Infect Dis 1980; 142: 660–664.

    PubMed  CAS  Google Scholar 

  11. Brandt CD, Kim HW, Rodriguez WJ, et al: Pediatric viral gastroenteritis during eight years of study. J Clin Microbiol 1983; 18: 71–78.

    PubMed  CAS  Google Scholar 

  12. Brandt CD, Parrot RH, Chandra R, et al: Diarrhea virus and sudden infant deaths. Pediatr Res, abstract 1068

    Google Scholar 

  13. Bridger JC: Novel rotaviruses in animals and man, in Ciba Foundation Sym¬posium 128: Novel Diarrhoea Viruses. New York, Wiley, 1987, pp 5–15.

    Google Scholar 

  14. Bryden AS, Thouless ME, Flewett TH: Rotavirus in rabbits. Vet Rec 1976; 99: 323.

    PubMed  CAS  Google Scholar 

  15. Buffet-Janvresse C, Berhard E, Magard H: Responsabilité des rotavirus dans les diarrhees du nourissan. Nouv Presse Med 1976; 5: 1249–1251.

    PubMed  CAS  Google Scholar 

  16. Chiba S, Yokoyama T, Nakata S, et al: Protective effect of naturally acquired hemotypic and hetertypic rotavirus antibodies. Lancet 1986; 2: 417–421.

    PubMed  CAS  Google Scholar 

  17. Christy C, Madore HP, Treanor JJ, Pray K, Kapikian AZ, Chanock RM, Dolin R: Safety and immunogenicity of live attenuated rhesus monkey ro-tavirus vaccin.J Infect Dis 1986; 154: 1045–1047.

    PubMed  CAS  Google Scholar 

  18. Deerlove J, Lathan P, Deerlove B, et al: Clinical range of neonatal rotavirus gastroenteritis. Br Med J 1983; 286: 1473–1475.

    Google Scholar 

  19. De Lage G, McLaughlin B, Berthiaume L: A clinical study of rotavirus gas-troenteritis.J Pediatr 1978; 93: 455–457

    Google Scholar 

  20. De Mol P, Zissis G, Butzler JP: Failure of live attenuated oral rotavirus vac-cine. Lancet 1986; 2: 108.

    PubMed  Google Scholar 

  21. Dingle JH, Badger GF, Jordan WS: Illness in the Home: A Study of 25,000 Illnesses in a Group of Cleveland Families. Cleveland, Western Reserve University Press, 1964, pp 19–32

    Google Scholar 

  22. Dominick HC, Maas G: Rotavirus infectionen im kindersalter. Klin Paediatr 1979; 191: 33–39.

    CAS  Google Scholar 

  23. Eugster AK, Strother J, Hartfield DA: Rotavirus (reovirus-like) infection of neonatal ruminants in a zoo nursery. J Wild Dis 1978; 14: 351–354.

    CAS  Google Scholar 

  24. Flewett TH: Clinical features of rotavirus infections, in Tyrell DAJ, Kapikian AZ (eds): Virus Infections of the Gastrointestinal Tract. New York, Marcel Dekker, 1982, pp 125–145.

    Google Scholar 

  25. Flewett TH, Bryden AS, Davies H: Virus particles in gastroenteritis. Lancet 1973; 2: 1497.

    PubMed  CAS  Google Scholar 

  26. Flewett TH, Bryden AS, Davies H: Diarrhea in foals and other animals. Vet Rec 1975; 97: 477.

    Google Scholar 

  27. Flewett TH, Bryden AS, Davies H, et al: Relationship between virus from acute gastroenteritis of children and newborn calves. Lancet 1974; 2: 61–63.

    PubMed  CAS  Google Scholar 

  28. Flores J, Perez-Schael I, Gonzalez M, et al: Protection against severe rotavirus diarrhea by rhesus rotavirus vaccine in Venezuelan infants. Lancet 1987; 1: 882–884.

    PubMed  CAS  Google Scholar 

  29. Flores J, Perez I, White L, et al: Genetic relatedness among human rotaviruses as determined by RNA hybridization. Infect Dis 1982; 37: 648–655.

    CAS  Google Scholar 

  30. Fujita Y, Hiyoshi K, Wakasugi N, et al: Transient improvement of the West syndrome in two cases following rotavirus colitis. No To Hattutsu1988;20:59– 63

    Google Scholar 

  31. Gordon AG: Rotavirus infections and the sompe syndrome. J Infect Dis 1982; 146: 117–118.

    PubMed  CAS  Google Scholar 

  32. Greenberg HB, Valdesuso J, Yolken RH, et al: Role of Norwalk virus in outbreaks of nonbacterial gastroenteritis. J Infect Dis 1979; 139: 564–568.

    PubMed  CAS  Google Scholar 

  33. Grunow JE, Dunton SF, Waner JL: Human rotavirus-like particles in hepatic abscess. J Pediatr 1985; 106: 73–76.

    PubMed  CAS  Google Scholar 

  34. Gurwith M, Wenman W, Hinde E, et al: A prospective study of rotavirus infection in infants and young children. J Infect Dis 1981; 144: 218–224.

    PubMed  CAS  Google Scholar 

  35. Halsey N, Galazka A: The effectiveness of DPT and oral poliomyelitis im-munization schedules initiated from birth to 12 weeks of age. Bull WHO 1985; 63: 1151–1169.

    PubMed  CAS  Google Scholar 

  36. Hanlon P, Hanlon L, Marsh V, et al: Trial of an attenuated bovine rotavirus vaccine (RIT 4237) in Gambian infants. Lancet 1987; 1: 1342–1345.

    PubMed  CAS  Google Scholar 

  37. Hjelt K, Graubelle PC, Anderson L, et al: Antibody response in serum and intestine in children up to six months after a naturally acquired rotavirus gastroenteritis. J Pediatr Gastroenterol Nutr 1986; 5: 74–80.

    PubMed  CAS  Google Scholar 

  38. Holt PA, Steel AE, Armstrong AM: Transient hyperphosphatasaemia of in-fancy following rotavirus infection. J Infect 1985; 9: 283–285.

    Google Scholar 

  39. Hoshino Y, Sereno MM, Midthun K, et al: Independent segregation of two antigenic specificities (VP3 and VP7) involved in neutralization of rotavirus infectivity. Proc Natl Acad Sci USA 1985; 82: 8701–8704.

    PubMed  CAS  Google Scholar 

  40. Hoshino Y, Wyatt RG, Flores J, et al: Serotypic characterization of rota-viruses derived from asymptomatic human neonatal infections. J Clin Mi-crobiol 1985; 21: 425–430.

    CAS  Google Scholar 

  41. Hoshino Y, Wyatt RG, Greenberg HB, et al: Serotypic similarity and diversity of rotaviruses of mammalian and avian origins as studied by plaque reduction neutralization. J Infect Dis 1984; 149: 694–702.

    PubMed  CAS  Google Scholar 

  42. Hung T, Chen G, Wang C, et al: Waterbourne outbreak of rotavirus diarrhea in adults in China caused by a novel rotavirus. Lancet 1984; 1: 1139–1142.

    PubMed  CAS  Google Scholar 

  43. Jarvis WR, Middleton PJ, Gelfand EW: Significance of viral infections in severe combined immunodeficiency disease. Pediatr Infect Dis 1983;2:187–192

    PubMed  CAS  Google Scholar 

  44. Jones RC, Hughes CS, Henry RR: Rotavirus infection in commercial laying hens. Vet Rec 1979; 104: 22.

    PubMed  CAS  Google Scholar 

  45. Kapikian AZ, Chanock RM: Rotaviruses, in Fields BN, et al (eds): Virology. New York, Raven Press, 1985, pp 863–906.

    Google Scholar 

  46. Kapikian AZ, Chanock RM: Norwalk group of viruses, in Fields BN, et al (eds): Virology. New York, Raven Press, 1985, pp 1495–1517.

    Google Scholar 

  47. Kapikian AZ, Cline WL, Kim HW, et al: Antigenic relationships among five reovirus-like (RVL) agents by complement fixation (CF) and development of a new substitute CF antigen for the human RVL agent of infantile gas-troenteritis. Proc Soc Exp Biol Med 1976; 152: 535–539.

    PubMed  CAS  Google Scholar 

  48. Kapikian AZ, Cline WL, Mebus CA, et al: New complement-fixation test for the human reovirus-like agent of infantile gastroenteritis: Nebraska calf diarrhoea virus used as antigen. Lancet 1975; 1: 1056–1061.

    PubMed  CAS  Google Scholar 

  49. Kapikian AZ, Flores J, Hoshino Y, et al: Rotavirus: the major etiologic agent of severe infantile diarrhea may be controllable by a “jennerian” approach to vaccination. J Infect Dis 1986; 153: 815–822.

    PubMed  CAS  Google Scholar 

  50. Kapikian AZ, Flores J, Hoshino Y, et al: Rotavirus: the major etiologic agent of severe infantile diarrhea may be controllable by a “jennerian” approach to vaccination. J Infect Dis 1986; 153: 815–822.

    PubMed  CAS  Google Scholar 

  51. Kapikian AZ, Flores J, Midthun K, et al: Development of a rotavirus vaccine by a “Jennerian” and modified “Jennerian” approach. Vaccines 88 Cold Spring Harbor, New York, Cold Spring Harbor Laboratory, 1988, pp 151–158.

    Google Scholar 

  52. Kapikian AZ, Hoshino Y, Flores J, et al: Alternative approaches to the de-velopment of a rotavirus vaccine, in Holmgren J, Lindberg A, Mollby R (eds): Development of Vaccines and Drugs Against Diarrhea. 11th Nobel Conference, Stockholm, 1985. Lund, Studentlitteratur, 1986, pp 192– 214

    Google Scholar 

  53. Kapikian AZ, Kalica AR, Shih JW, et al: Buoyant density in cesium chloride of the human reovirus-like agent of infantile gastroenteritis by ultracentri- fugation, electron microscopy, and complement-fixation. Virology 1976;70:564– 569.

    Google Scholar 

  54. Kapikian AZ, Kim HW, Wyatt RG, et al: Human reovirus-like agent as the major pathogen associated with “winter” gastroenteritis in hospitalized infants and young children. N Engl J Med 1976,294:965– 972

    PubMed  Google Scholar 

  55. Kapikian AZ, Kim HW, Wyatt RG, et al: Reovirus-like agent in stools: as-sociation with infantile diarrhea and development of serologic tests. Science 1974;185:1049– 1053

    PubMed  Google Scholar 

  56. Kapikian AZ, Midthun K, Hoshino Y, et al: Rhesus rotavirus: a candidate vaccine for prevention of human reovirus disease, in Lerner RA, Chanock RM, Brown F (eds): Vaccines 85: Molecular and Chemical Basis of Resistance to Parasitic, Bacterial, and Viral Diseases. Cold Spring Harbor, New York, Cold Spring Harbor Laboratory, 1985, pp 357– 367

    Google Scholar 

  57. Kapikian AZ, Wyatt RG, Dolin R, et al: Visualization by immune electron microscopy of a 27nm particle associated with acute infectious non-bacterial gastroenteritis. J Virol 1972;10:1075–1081

    PubMed  CAS  Google Scholar 

  58. Kaplan JE, Gary GW, Baron RC, et al: Epidemiology of Norwalk gastroen-teritis and the role of Norwalk virus in outbreaks of acute nonbacterial gas-troenteritis. Ann Intern Med 1982;96:756–761.

    PubMed  CAS  Google Scholar 

  59. Kim HW, Brandt CD, Kapikian AZ, et al: Human reovirus-like agent (HRULA) infection: occurrence in adult contacts of pediatric patients with gastroenteritis. JAMA 1977;238:404– 407

    PubMed  Google Scholar 

  60. Konno T, Suzuki H, Kutsushima N, et al: Influence of temperature and relative humidity on human rotavirus infection in Japan. J Infect Dis 1983;147:125– 128.

    Google Scholar 

  61. Konno T, Suzuki H, Kutsuzawa T, et al: Human rotavirus and intussusception. N Engl J Med 1977;297:945.

    PubMed  CAS  Google Scholar 

  62. Konno T, Suzuki H, Kutsuzawa T, et al: Human rotavirus infection in infants and young children with intussusception. J Med Virol 1978;2:265– 269

    PubMed  Google Scholar 

  63. Konno T, Suzuki H, Kutsushima N, et al: Influence of temperature and relative humidity on human rotavirus infection in Japan. J Infect Dis 1983;147:125– 128

    PubMed  Google Scholar 

  64. Lanata CF, Black RE, del Aguila, et al: Protection of Peruvian children against rotavirus diarrhea of specific serotypes by RIT 4237 attenuated bovine vaccine. J Infect Dis (in press).

    Google Scholar 

  65. Lewis HM, Parry JV, Davies HA, et al: A year’s experience of the rota¬virus system and its association with respiratory illness. Arch Dis Child 1979; 54: 339–346.

    PubMed  CAS  Google Scholar 

  66. Losonsky GA, Rennels MB, Kapikian AZ, et al: Safety, infectivity, trans- missibility, and immunogenicity of rhesus rotavirus vaccine (MMU 18006) in infants. Pediatr Infect Dis 1986; 5: 25–29.

    PubMed  CAS  Google Scholar 

  67. Malherbe HH, Strickland-Cholmley M: Simian rotavirus SA-11 and the re-lated “O” agent. Arch Ges Virusforsch 1967; 22: 235–245.

    PubMed  CAS  Google Scholar 

  68. Matsuno S, Hasegawa A, Mukoyama A, Inouye S: A candidate for a new serotype of human rotavirus. J Virol 1985; 54: 623–624.

    PubMed  CAS  Google Scholar 

  69. Matsuno S, Murakami S, Takagi M, et al: Cold adaption of human rotavirus. Virus Res 1987; 7: 273–280.

    PubMed  CAS  Google Scholar 

  70. Matsuno S, Utagawa E, Sugiura A: Association of rotavirus infection with Kawasaki syndrome. J Infect Dis 1983; 148: 177.

    PubMed  CAS  Google Scholar 

  71. McCormack JG: Clinical features of a rotavirus gastroenteritis. J Infect Dis 1982; 4: 167–174.

    CAS  Google Scholar 

  72. McNulty MS, Allan GM, Stuart JC: Rotavirus infection in avian species. Vet Ree 1978; 103: 319–320.

    CAS  Google Scholar 

  73. Mebus CA, Underdahl NR, Rhodes MG, Twiehaus MJ: Calf diarrhea (scours): reproduced with a virus from a field outbreak. Univ Nebraska Res Bull 1969; 233: 1–16.

    Google Scholar 

  74. Midthun K, Greenberg HB, Hoshino Y, et al: Reassortant rotaviruses as potential live rotavirus vaccine candidates. J Virol 1985; 53: 949–954.

    PubMed  CAS  Google Scholar 

  75. Midthun K, Hoshino Y, Kapikian AZ, Chanock RM: Single gene substitution rotavirus reassortants containing the major neutralization protein (VP7) of human rotavirus serotype 4. J Clin Microbiol 1986; 24: 822–826.

    PubMed  CAS  Google Scholar 

  76. Much D, Zajac I: Purification and characterization of epizootic diarrhea of infant mice virus. Infect Immun 1972; 6: 1019–1024.

    PubMed  CAS  Google Scholar 

  77. Nigro G and Midulla M: Acute laryngitis associated with rotavirus gastroen¬teritis. J Infect 1983; 7: 81–83.

    PubMed  CAS  Google Scholar 

  78. Offit PA, Clark HF, Blavat G, Greenberg HB: Reassortant rotaviruses con¬taining structural proteins: VP3 and VP7 from different parents induce an¬tibodies protective against each parental serotype. J Virol 1986; 60: 491–496.

    PubMed  CAS  Google Scholar 

  79. Ohno A, Taniguchi K, Sugimoto K, et al: Rotavirus gastroenteritis and afe¬brile infantile convulsion. No To Hattatsu 1982; 14: 520–521.

    Google Scholar 

  80. Perez-Schael I, Gonzalez M, Daoud N, et al: Reactogenicity and antigen-icity of the rhesus rotavirus vaccine in Venezuelan children. J Infect Dis 1987; 155: 334–337.

    PubMed  CAS  Google Scholar 

  81. Reed DE, Daley CA, Shave HJ: Reo virus-like agent associated with neonatal diarrhea in pronghorn antelope. J Wild Dis 1976; 12: 488–491.

    CAS  Google Scholar 

  82. Rennels MB, Losonsky GA, Le vine MM, et al: Preliminary evaluation of the efficacy of rhesus rotavirus vaccine strain MMU 18006 in young children. Pediatr Infect Dis 1987; 5: 587–588.

    Google Scholar 

  83. Rodriguez WJ, Kim HW, Arrobio JO, et al: Clinical features of acute gas-troenteritis associated with human reovirus-like agent in infants and young children. J Pediatr 1977; 91: 188–193.

    PubMed  CAS  Google Scholar 

  84. Roger SM, Craven JA, William I: Demonstration of reovirus-like particles in intestinal contents of piglets with diarrhea. Austr Vet J 1975; 51: 536.

    Google Scholar 

  85. Roseto A, Lema F, Sitbon M, et al: Detection of rotavirus in dogs. Soc Occup Med 1979; 7: 478.

    Google Scholar 

  86. Rotbart HA, Levin MJ, Yolken RH, et al: An outbreak of rotavirus-associated neonatal necrotizing enterocolitis. J Pediatr 1983; 103: 454–459.

    PubMed  CAS  Google Scholar 

  87. Rotbart HA, Nelson WL, Glode MP, et al: Neonatal rotavirus-associated necrotizing enterocolitis: case control study and prospective purveillance during an outbreak. J Pediatr 1988; 112: 87–93.

    PubMed  CAS  Google Scholar 

  88. Ryder R, Singh N, Reeves WC, et al: Evidence of immunity induced by naturally acquired rotavirus and Norwalk virus infection on two remote Panamanian islands. J Infect Dis 1985; 151: 99–105.

    PubMed  CAS  Google Scholar 

  89. Saitoh Y, Matsuno S, Mukuyoma A: Exanthem subitum and rotavirus. N Engl J Med 1983; 304: 845.

    Google Scholar 

  90. Salmi TT, Arstila P, Koivikko A: Central nervous system invovlement in patients with rotavirus gastroenteritis. Scand J Infect Dis 1978; 10: 29–31.

    PubMed  CAS  Google Scholar 

  91. Santosham M, Yolken RH, Quiroz E, et al: Detection of rotavirus in respiratory secretions of children with pneumonia. J Pediatr 1983; 103: 583–585.

    PubMed  CAS  Google Scholar 

  92. Sato K, Inaba Y, Shinozaki T, et al: Isolation of human rotavirus in cell cultures. Arch Virol 1981; 69: 155–160.

    PubMed  CAS  Google Scholar 

  93. Saulsbury FT, Winkelstein JA, Yolken RH: Chronic rotavirus infection in immunodeficiency. J Pediatr 1980; 97: 61–65.

    PubMed  CAS  Google Scholar 

  94. Scott AC, Luddington J, Lucas M, Gilbert FR: Rotavirus in goats. Vet Ree 1978; 103: 145.

    CAS  Google Scholar 

  95. Shepherd RW, Truslow S, Walker-Smith JA, et al: Infantile gastroenteritis: a clinical study of reovirus-like agent infection. Lancet 1975; 2: 1082–1083.

    PubMed  CAS  Google Scholar 

  96. Snodgrass DR, Angus KW, Gray EW: A rotavirus from kittens. Vet Ree 1979; 104: 222–223.

    CAS  Google Scholar 

  97. Snodgrass DR, Smith W, Gray EW, Herring JA: A rotavirus in lambs with diarrhea. Res Vet Sei 1976; 20: 113–114.

    CAS  Google Scholar 

  98. Snodgrass DR, Wells PW: Passive immunity in rotaviral infections. J Am Vet Med Assoc 1978; 173: 565–568.

    PubMed  CAS  Google Scholar 

  99. Snyder JD, Merson MH: The magnitude of the global problem of acute diar- rhoeal disease: a review of active surveillance data. Bull WHO 1982;60:605– 613.

    Google Scholar 

  100. Stoll BJ, Glass RI, Huq MI, et al: Surveillance of patients attending a diarrheal disease hospital in Bangladesh. Br Med J 1982; 285: 1185–1188.

    CAS  Google Scholar 

  101. Stoll BJ, Glass RI, Banu H, et al: Value of stool examination in patients with diarrhea. Br Med J 1983; 286: 2037–2040.

    CAS  Google Scholar 

  102. Stuker G, Oshiro L, Schmidt NL: Antigenic comparisons of two new rotaviruses from rhesus monkeys. J Clin Microbiol 1980; 11: 202–203.

    PubMed  CAS  Google Scholar 

  103. Tallett S, MacKenzie C, Middleton A, et al: Clinical, laboratory, epidemiological features of viral gastroenteritis in infants and children. Pediatrics 1977; 60: 217–222.

    PubMed  CAS  Google Scholar 

  104. Taylor PR, Merson MH, Black RE, et al: Oral rehydration therapy for treatment of rotavirus diarrhea in a rural treatment centre in Bangladesh. Archiv Dis Childhood 1980; 55: 376–379.

    CAS  Google Scholar 

  105. Tzipori S, Caple IW, Butler R: Isolation of a rotavirus from deer. Vet Ree 1976; 99: 398.

    CAS  Google Scholar 

  106. Urasawa T, Urasawa S, Taniguchi K: Sequential passages of human rotavirus in MA-104 cells. Microbiol Immunol 1981; 25: 1025–1035.

    PubMed  CAS  Google Scholar 

  107. Ushijima H, Bosu K, Abe T, Shinozaki T: Suspected rotavirus encephalitis. Archiv Dis Childhood 1986; 61: 692–694.

    CAS  Google Scholar 

  108. Ushijima H, Tajima T, Tagaya M, et al: Rotavirus and central nervous system. Brain and Development 1984; 6: 138.

    Google Scholar 

  109. Ushijima H, Araki K, Abe T, Shinozaki T: Anti-rotavirus antibody in cerebrospinal fluid. Archiv Dis Childhood 1987; 62: 298–299.

    CAS  Google Scholar 

  110. Vesikari T, Isolauri E, Delem A, et al: Clinical efficacy of the RIT 4237 live attenuated bovine rotavirus vaccine in infants vaccinated before a rotavirus epidemic. J Pediatr 1985; 107: 189–194.

    PubMed  CAS  Google Scholar 

  111. Vesikari T, Isolauri E, D’Hondt E, et al: Increased take rate of oral rotavirus vaccine in infants after milk feeding. Lancet 1984; 2: 700.

    PubMed  CAS  Google Scholar 

  112. Vesikari T, Isolauri E, D’Hondt E, et al: Protection of infants against rotavirus diarrhea by RIT 4237 attenuated bovine rotavirus strain vaccine. Lancet 1984; 1: 977–981.

    PubMed  CAS  Google Scholar 

  113. Vesikari T, Kapikian AZ, Delem A, Zissis G: A comparative trial of rhesus monkey (RRV-1) and bovine (RIT 4237) oral rotavirus vaccines in young children. J Infect Dis 1986; 153: 832–839.

    PubMed  CAS  Google Scholar 

  114. Vesikari T, Rautanen T, Isolauri E, et al: Immunogenicity and safety of a low passage level bovine rotavirus candidate vaccine RIT 4256 in human adults and young infants. Vaccine 1987; 5: 105–108.

    PubMed  CAS  Google Scholar 

  115. Wallace RE, Vasington PJ, Petricciani JC, et al: Development of a diploid cell line from fetal rhesus monkey lung for virus vaccine production. In Vitro 1973; 8: 323–332.

    PubMed  CAS  Google Scholar 

  116. Walsh JA, Warren KS: Selective primary health care: an interim strategy for disease control in developing countries. N Engl J Med 1979,301:967– 974

    PubMed  Google Scholar 

  117. Woode GN, Bridger JC, Jones JM, et al: Morphological and antigenic re-lationships between viruses (rotaviruses) from acute gastroenteritis of children, calves, piglets, mice and foals. Infect Immun 1976; 14: 804–810.

    PubMed  CAS  Google Scholar 

  118. Wong CJ, Price Z, Bruckner DA: Aseptic meningitis in an infant with ro-tavirus gastroenteritis. Pediatr Infect Dis 1986; 3: 244–246.

    Google Scholar 

  119. WHO Scientific Working Group: Rotavirus and other viral diarrhoeas. Bull WHO 1980; 58: 183–198.

    Google Scholar 

  120. Wright PF, Tajima T, Thompson J, et al: Candidate rotavirus vaccine (rhesus rotavirus strain) in children: an evaluation. Pediatrics? 1987; 80: 473–480.

    PubMed  CAS  Google Scholar 

  121. Wyatt RG, Greenberg HB, James WD, et al: Definition of human rotavirus serotypes by plaque reduction assay. Infect Immun 1984; 37: 110–115.

    Google Scholar 

  122. Wyatt RG, Kapikian AZ, Hoshino Y, et al: Development of rotavirus vac-cines, in Control and Eradication of Infectious Diseases. An International Symposium. Washington, DC: Pan American Health Organization, 1985, pp 17–28.

    Google Scholar 

  123. Wyatt RG, Kapikian AZ, Mebus CA: Induction of cross-reactive serum neu¬tralizing antibody to human rotavirus in calves after in utero administration of bovine rotavirus. J Clin Microbiol 1983; 18: 505–508.

    PubMed  CAS  Google Scholar 

  124. Wyatt RG, Mebus CA, Yolken RH, et al: Rotaviral immunity in gnotobiotic calves: heterologous resistance to human virus induced by bovine virus. Science 1979; 203: 548–550.

    PubMed  CAS  Google Scholar 

  125. Yolken RH, Bishop CA, Townsend TR, et al: Infectious gastroenteritis in bone-marrow transplant recipients. N Engl J Med 1982; 306: 1009–1012.

    Google Scholar 

  126. Yolken RH, Murphy M: Sudden infant death syndrome associated with ro¬tavirus infection. J Med Virol 1982; 10: 291–296.

    PubMed  CAS  Google Scholar 

  127. Yow MD, Melnick JL, Blattner RJ, et al: The association of viruses and bacteria with infantile diarrhea. Am J Epidemiol 1970; 92: 33–39.

    PubMed  CAS  Google Scholar 

  128. Zissis G: Het belang van rotavirus in die etiologie van infantiele diaree. MD thesis. Vrije Universiteit, Brussels, 1979.

    Google Scholar 

  129. Zissis G, Lambert JP, Marbehant P, et al: Protection studies in colostrum- deprived piglets of a bovine rotavirus vaccine candidate using human rotavirus strains for challenge. J Infect Dis 1983; 148: 1061–1068.

    PubMed  CAS  Google Scholar 

Download references

Authors
  1. Albert Z. Kapikian
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Jorge Flores
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yasutaka Hoshino
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Karen Midthun
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Kim Y. Green
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Mario Gorziglia
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Robert M. Chanock
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Louis Potash
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Irene Perez-Schael
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. Marino Gonzalez
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. Timo Vesikari
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. Leif Gothefors
    View author publications

    You can also search for this author in PubMed Google Scholar

  13. Goran Wadell
    View author publications

    You can also search for this author in PubMed Google Scholar

  14. Roger I. Glass
    View author publications

    You can also search for this author in PubMed Google Scholar

  15. Myron M. Levine
    View author publications

    You can also search for this author in PubMed Google Scholar

  16. Margaret B. Rennels
    View author publications

    You can also search for this author in PubMed Google Scholar

  17. Genevieve A. Losonsky
    View author publications

    You can also search for this author in PubMed Google Scholar

  18. Christy Cynthia
    View author publications

    You can also search for this author in PubMed Google Scholar

  19. Raphael Dolin
    View author publications

    You can also search for this author in PubMed Google Scholar

  20. Edwin L. Anderson
    View author publications

    You can also search for this author in PubMed Google Scholar

  21. Robert B. Belshe
    View author publications

    You can also search for this author in PubMed Google Scholar

  22. Peter F. Wright
    View author publications

    You can also search for this author in PubMed Google Scholar

  23. Mathuram Santosham
    View author publications

    You can also search for this author in PubMed Google Scholar

  24. Neal A. Halsey
    View author publications

    You can also search for this author in PubMed Google Scholar

  25. Mary Lou Clements
    View author publications

    You can also search for this author in PubMed Google Scholar

  26. Stephen D. Sears
    View author publications

    You can also search for this author in PubMed Google Scholar

  27. Marc C. Steinhoff
    View author publications

    You can also search for this author in PubMed Google Scholar

  28. Robert E. Black
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. National Institute of Immunology, JNU Complex, Shahid Jeet Singh Marg, 110 067, New Delhi, India

    G. P. Talwar

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag New York Inc.

About this paper

Cite this paper

Kapikian, A.Z. et al. (1989). Rationale for the Development of a Rotavirus Vaccine for Infants and Young Children. In: Talwar, G.P. (eds) Progress in Vaccinology. Progress in Vaccinology, vol 2. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3508-8_17

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-3508-8_17

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-96734-9

  • Online ISBN: 978-1-4612-3508-8

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation