Elasticity of Pulmonary Blood Vessels in Human Lungs
The mechanical properties of pulmonary blood vessels are essential factors influencing the distribution of pulmonary blood flow, regional volume distribution of blood and pulse wave propagation throughout the lung. These properties affect the pressure-flow relationship, and the change in total blood volume in response to an alteration in blood pressure. In order to formulate such problems, mechanical property data for blood vessels of all generations of the human lung are needed and are gathered in our laboratory. In particular, vessel diameter as a function of transmural pressure are measured for each vessel generation.
KeywordsCellulose Barium Dextran Photography Barium Sulfate
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- Bachofen M, Weibel ER, Roos B (1975) Postmortem fixation of human lungs for electron microscopy. Am Rev Respir Dis IIIi:247–256.Google Scholar
- Patel DJ, Vaishnav RN (1972) The rheology of large blood vessels. In Bergel DH (ed)Cardiovascular Fluid Dynamics, Academic Press, New York: 22–65.Google Scholar
- Sugihara T, Martin CJ, Hildebrant (1971) Length-tension properties of the alveolar wall in man. J Appl Physiol 30:874–878.Google Scholar
- Yen RT, Sobin SS (1988) Elasticity of arterioles and venules in postmortem human lungs. J Appl Physiol 64:611–619.Google Scholar