Abstract
The structure and function of tendons and ligaments are intimately interrelated. The structural arrangement of these parallel-fibered collagenous tissues is similar to rope-building; from the α chains in the collagen molecule itself up to the level of fibrils the principle is thus helicality that changes handedness on consecutive levels of organization. This arrangement, which is comparable to rope-tightening, renders stability and strength to the tissue - collagen is the strongest protein in the mammalian organism. On higher levels of organization there is “only” planar waviness, which contributes to the properties during the initial part of the stress-strain curve.
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References
Akerblom B: Standing and Sitting Posture. Stockholm, Nordiska Bokhandeln, 1948.
Akeson WH, Woo SL-Y Maiel D, Matthews JV: Biomechanical and biochemical changes in the periarticular connective tissue during contracture development in the immobilized rabbit knee. Conn Tiss Res 1974;2:315–323.
Akeson WH, Amiel D, Mechanic GL, Woo SL-Y, Harwood FL & Hamer ML: Collagen cross-linking alterations in joint contractures: Changes in the reducible cross-links in periarticular connective tissue collagen after nine weeks of immobilization. Conn Tiss Res 1977;5:15–20.
Alexander RM: Visco-elastic properties of the body-wall of sea anemones. J exp Biol 1962;39:373–386.
Alfrey T, Gurnee EF: Molecular structure and mechanical behaviour of macromolecules, in Remington JW (ed): Tissue Elasticity. Washington, Amer Phys Soc, 1957; 12–32.
Arcadi: Quoted from Hansen TM: Cyclophosphamide and Collagen. Copenhagen, Laegeforeningens Forlag, 1979.
Bailey AJ, Etherington DJ: Metabolism of collagen and elastin, in Florkin M, Neuberger A (eds): Comprehensive Biochemistry, Vol 19B, Part I, Protein Metabolism. Amsterdam, Elsevier, 1980, pp 299–408.
Barenberg SA, Filisko FE Geil PH: Ultrastructural deformation of collagen. Conn Tiss Res 1878;6:25–35.
Barfred T: Experimental rupture of the achilles tendon. Acta Orthop Scand 1971a;42:528–543.
Barfred T: Kinesiological comments on subcutaneous ruptures of the achilles tendon. Acta Orthop Scand 1971b;42:397–405.
Barnes GRG, Pinder DN: In vivo tendon tension and bone strain measurement and correlation. J Biomechanics 1974;7:35–42.
Booth FW, Tipton CM: Effects of training and 17-B estradiol upon heart rates, organ weights, and ligamentous strength of female rats. Intern Zschr angew Physiol 1969;27:187–197.
Brodsky B, Tamaka S, Eikenberry EF: X-ray diffraction as a tool for studying collagen structure, in Nimni ME (ed): Collagen Vol I Biochemistry. Boca Raton, CRC Press, 1988, pp 95–112.
Carlstedt CA: Mechanical and chemical factors in tendon healing. Effects of indomethacin and surgery in the rabbit. Acta Orthop Scand 1987;58:Suppl 224. Clark JM, Sidles JA: The interrelation of fiber bundles in the anterior cruciate ligament. J Orthop Res 1990;8:180–188.
Cohen RE, Hooley CJ, McCrum NG: The mechanism of the viscoelastic deformation of collagenous tissue. Nature 1974,247:59–61.
Cohen RE, Hooley CJ, McCrum NG: Mechanism of the viscoelastic deformation of collagenous tissue, in Atkins EDT, Keller A (eds): Structure of Fibrous Biopolymers. London, Butterworths, 1975, pp 251–254.
Cohen RE, Hooley CJ, McCrum NG: Viscoelastic creep of collagenous tissue. J Biomechanics 1976:9:175–184.
Cohen RE, Hooley CJ: A model for creep behaviour of tendon. Int J Biol Macromol 1979;1:123–132.
Cowan PM, North ACT, Randall JT: X-ray diffraction studies of collagen fibres. Symp Soc Exp H Biol 1955;9:115–126.
Davidsson L: tiber die subkutanen Sehnen-Rupturen und die Regeneration der Sehne. Ann Chir Gynaec Fenniae 1956; Suppl 6.
Diamant J, Keller A, Baer E, Litt M, Arridge RGC: Collagen: ultrastructure and its relation to mechanical properties as a function of ageing. Proc Roy Soc Lond B 1972;180:293–315.
Elden HR: Physical properties of collagen fibers, in Hall DA (ed): International Review of Connective Tissue Research, Vol 4. New York, Academic Press, 1968, pp 283–348.
Elliott DH, Crawford GNC: The thickness and collagen content of tendon relative to the strength and cross-sectional area of muscle. Proc Roy Soc Lond B 1965;162:137–146.
Frank C, Woo SL-Y, Amiel D, Harwood F, Gomez M, Akeson W: Medial collateral ligament healing. A multidisciplinary assessment in rabbits. Am J Sports Med 1983a; 11:379–389.
Frank C, Amiel D, Akeson WH: Healing of the medial collateral ligament of the knee. A morphological and biochemical assessment in rabbits. Acta Orthop Scand 1983b;54:917–923.
Frank C, Schachar N, Dittrich D, Shrive N, DeHaas W, Edwards G: Electromagnetic stimulation of ligament healing in rabbits. Clin Orthop Rel Res 1983c; 175:263–272.
Frank C, Woo SL-Y, Andriacchi T, Brand R, Oakes B, Dahners L, DeHaven K, Lewis J, Sabiston P: Normal ligament: structure, function, and composition, in Woo SL-Y, Buckwalter JA (eds): Injury and Repair of the Musculoskeletal Soft Tissues. Park Ridge, American Academy of Orthopaedic Surgeons, 1987, pp 45–101.
Frisén M, Magi M, Sonnerup L, Viidik A: Rheological analysis of soft collagenous tissues. Part I: Theoretical considerations. J Biomechanics 1969;2:13–20.
Frisén M. Magi M, Sonnerup L, Viidik a: Rheological analysis of soft collagenous tissues. Part II: Experimental evaluations and verifications. J Biomechanics 1969;2:21–28.
Fung YCB: Elasticity of soft tissues in simple elongation. Amer J Physiol 1967;213: 1552–1544.
Fung YCB: Biomechanics, its scope, history and some problems of continuum mechanics in physiology. App Mech Rev 1968;21-l-20.
Fung YCB: Stress-strain history relations of soft tissues in simple elongation, in Fung YCB, Perrone N, Anliker M (eds): Biomechanics: its foundations and objectives. Englewood Cliffs, Prentice-Hall, 1972, pp 181–208.
Fung YC: Biomechanics - Mechanical properties of living tissues. New York, Springer-Verlag, 1981.
Gathercole LJ, Keller A: X-ray diffraction effects related to superstructure in rat tail tendon collagen. Biochim Biophys Acta 1978;535:253–271.
Gathercole LJ, Keller A, Shah JS: The periodic pattern in native tendon collagen; correlation of polarizing with scanning electron microscopy. J Microscopy 1974;102:95–106.
Gelbermann R, Goldberg V, An K-N, Banes A: Tendon, in Woo SL-Y, Buckwalter JA (eds): Injury and Repair of the Musculoskeletal Soft Tissues. Park Ridge, American Academy of Orthopaedic Surgeons, 1987, pp 5–40.
Gelberman RH, Woo SL-Y, Lothringer K, Akeson WH, Amiel D: Effects of early intermittent passive mobilization on healing canine flexor tendons. J Hand Surg 1982;7:170–175.
Gräfe H: Aspekte zur Ätiologie der subkutanen Achillessehnenruptur. Zbl Chir 1969;94:1073–1082.
Haut RC, Little RW: A constitutive equation for collagen fibers. J Biomechanics 1972;5:423–430.
Harkness RD: Mechanical properties of collagenous tissues, in Gold BS (ed): Treatise on Collagen, Vol 2 Biology of Collagen Part A. London, Academic Press, 1968, pp 247–310.
Hirsch G: Tensile properties during tendon healing. Acta Orthop Scand 1974;Suppl 153.
Hooley CJ: The Viscoelastic Behaviour of Tendon, thesis, Oxford University, 1977.
Hutton P, Ferris B: in Bucknail TE, Ellis H (eds): Wound Healing for Surgeons. London, Balliere Tindall, 1984, pp 286–296.
Kennedy JC, Hawkins RJ, Willis RB: Strain gauge analysis of knee ligaments. Clin Orthop Rel Res 1977;129:225–229.
Kiiskinen A: Physical training and connective tissues in young mice. Physical properties of Achilles tendons and long bones. Growth 1977;44:123–137.
Kiiskinen A, Heikkinen E:Physical training and connective tissues in young mice. Brit J Derm 1976;95:525–529.
Labat-Robert J, Robert L: Interactions between structural glycoproteins and collagen, in Nimni ME (ed): Collagen, Vol I Biochemistry, Boca Raton, CRC Press, 1988,173–186.
Laos GS, Tipton CM, Cooper RR: Influence of physical activity on ligament insertions in the knees of dogs. J Bone Joint Surg 1971;53A:275–286.
Larsen AQ, Viidik A: The influence of diclofenac sodium and indomethacin on healing incisional wounds in skin. Eur Surg Res 1988;20:Suppl 1:58–59.
Larsen NP, Forwood MR, Parker AW: Immobilization and retraining of cruciate ligaments in the rat. Acta Orthop Scand 1987;58:260–264.
Lewis JL: A note on the application and evaluation of the buckle transducer for knee ligament force. J Biomech Engng 1982;104:125–128.
Morgan FR: The mechanical properties of collagen fibres: stress-strain curves. J Soc Leather Trades’ Chem 1960;44:170–182.
Nemetschek T, Jonak R, Nemetschek-Gansler H, Riedl H: Über die Bestimmung von Langperioden-Änderungen am Kollagen. Z Naturforsch 1978;33C:928–936.
Nimni ME, Harkness RD: Molecular structures and functions of collagen, in Nimni ME (ed): Collagen, Vol I Biochemistry. Boca Raton, CRC Press, 1988, pp 1–77.
Noyes FR: Functional properties of knee ligaments and alterations induced by immobilization. Clin Orthop Rel Res 1977;123:240–242.
Noyes FR, Torvik PJ, Hyde WB, De Lucas JL: Biomechanics of ligament failure. II: An analysis of immobilization, exercise and reconditioning effects in primates. J Bone Joint Surg 1974;56A:1406–1418.
Qurinia A, Viidik A: Hyperbaric oxygen improves the healing of ischaemic flaps but not incisional wounds in skin. Eur Surg Res 1989;21:Suppl 2:81–82.
Qurinia A, Viidik A: Design of an ischaemic double flap model, an investigation of blood flow and biomechanical properties, in Hvid I (ed): Proceedings of the 7th Meeting of the European Society of Biomechanics. Aarhus, Aarhus University, in press.
Riedl H, Nemetschek T, Jonak R: A mathematical model for the changes of the long-period structure in collagen, in Viidik A, Vuust J (eds): Biology of Collagen, London Academic Press, 1980, pp 289–296.
Ruggeri A, Benazzo F: Collagen-proteoglycan interaction, in Ruggeri a, Motta PM (eds): Ultrastructure of the Connective Tissue Matrix. Boston, Martinus Nijhoff, 1984, pp 113–125.
Rundgren Ä:Physical properties of connective tissue as influenced by single and repeated pregnancies in the rat. Acta Physiol Scand 1974;Suppl 417.
Simon PJ: The Mechanics of Tendon Function in Health and Disease, thesis, Massey University, Palmerston North, New Zealand, 1978.
Suominen H, Heikkinen E, Moisio H, Viljama K: Physical and chemical properties of skin in habitually trained and sedentary 31- to 70-year-old men. Brit J Derm 1978;99:147–154.
Stucke K: Über das elastische Verhalten der Achillessehne im Belastungsversuch. Langenbecks Arch klin Chir 1950;265:579–599.
Tipton CM, James SL, Mergner W, Tchang TK: Influence of exercise on strength of medial collateral knee ligaments of dogs. Am J Physiol 1970;218:894–901.
Tipton CM, Matthes RD, Sandage DS: In situ measurement of junction strength and ligament elongation in rats. J Appl Physiol 1974;37:758–761.
Viidik A: The effect of training on the tensile strength of isolated rabbit tendons. Scand J Plast Reconstr Surg 1967;1:141–147.
Viidik A: A rheological model for uncalcified parallel-fibred collagenous tissue. J Biomechanics 1968a; 1:3–11.
Viidik A: Elasticity and tensile strength of the anterior cruciate ligament in rabbits as influenced by training. Acta Physiol Scand 1968b;74:372–380.
Viidik A: Tensile properties of achilles tendon systems in trained and untrained rabbits. Acta Orthop Scand 1969;40:261–272.
Viidik A: Simultaneous mechanical and light microscopic studies of collagen fibers. Z Anat Entwickl-Ges 1972;136:204–212.
Viidik A: Functional properties of collagenous tissues, in Hall DA, Jackson DS (eds): International Review of Connective Tissue Research. New York, Academic Press, 1973;6:127–215.
Viidik A: On the correlation between structure and mechanical function of soft connective tissues. Verh Anat Ges 1978;72:75–89.
Viidik A: Connective tissues - possible implications of the temporal changes for the aging process. Mech Age Dev 1979a;9:267–285.
Viidik A: Biomechanical behavior of soft connective tissues, in Akkaç N (ed): Progress in Biomechanics. Alphen aan den Rijn, Sijthoff & Nordhoff, 1979b, pp 75–113.
Viidik A: Mechanical properties of parallel-fibred collagenous tissues, in Viidik A, Vuust J (eds): Biology of Collagen. London, Academic Press, 1980a, pp 237–255.
Viidik A: Interdependence between structure and function in collagenous tissues, in Viidik A, Vuust J (eds): Biology of Collagen. London, Academic Press, 1980b, pp 257–280.
Viidik A: Age-related changes in connective tissues, in Viidik A (ed): Lectures on Gerontology, Vol 1, Part A, On the Biology of Ageing. London, Academic Press, 1982, pp 173–211.
Viidik A. Adaptability of connective tissues, in Saltin B (ed): Biochemistry of Exercise - Metabolic Regulation and its Practical Significance. Camagne, Human Kinetics Publishers, 1986, pp 545–562.
Viidik A: Properties of tendons and ligaments, in Skalak R, Chien S (eds): Handbook of Bioengineering. New York, McGraw-Hill, 1987a, pp 6.1–6.19.
Viidik A: Biomechanics of tendons and other soft tissues - testing methods and structure-function interdependence, in Bergmann G, KOlbel R, Rohlmann A (eds): Biomechanics: Basic and applied Research. Dordrecht, Martinus Nijhoff, 1987b, pp 59–72.
Viidik A: Connections between muscle and bone, in Payne PA (ed): Concise Encyclopaedia on Biomedical and Biological Measurement Systems. Oxford, Pergamon Press, in press.
Viidik A, Danielsen CC, Oxlund H: On fundamental and phenomenological models, structure and mechanical properties of collagen, elastin and glycosaminoglycans. Biorheology 1982;19:437–451.
Viidik A, Ekholm R: Light and electron microscopic studies of collagen fibers under strain. Z Anat Entwickl-Ges 1968;127:154–164.
Viidik A, Gottrup F: Mechanics of healing soft tissue wounds, in Schmid-SchOnbein GR, Woo SL-Y, Zweifach BW (eds): Frontiers in Biomechanics. New York, Springer-Verlag, 1986, pp 262–279.
Viidik A, Sandqvist L, Mâgi M: Influence of postmortal storage on the tensile strength characteristics and histology of rabbit ligaments. Acta Orthop Scand 1965;Suppl 79.
Wertheim MG: Mémoire sur l’élasticité et la cohésion des principaux tissus du corps humain. Chim Phys 1947;21:385–414.
Woo SL-Y, Akeson WH, Amiel D, Convey FR, Matthews JV: The connective tissue response to immobility: A correlative study of the biomechanical and biochemical measurements of the normal and immobilized rabbit knee. Arth and Rheum 1975;18:257–264.
Woo SL-Y, Akeson WH, Jemmott GF: Measurements of nonhomogeneous directional mechanical properties of articular cartilage in tension using a video- dimensional analyzer. J Biomech 1976;9:785–791.
Woo SL-Y, Ritter MA, Maiel D, Sanders TM, Gomez MA, Kuei SC, Garfin SR, Akesson WH: The biomechanical and biochemical properties of swine tendons - long term effects of exercise on the digital extensors. Conn Tiss Res 1980;7:177–183.
Woo SL-Y, Gomez MA, Woo Y-K, Akeson WH: Mechanical properties of tendons and ligaments. II. The relationship between immobilization and exercise on tissue remodeling. Biorheology 1982;19:397–408.
Woo SL-Y, Gomez MA, Seguchi Y, Endo CM, Akeson WH: Measurement of mechanical properties of ligament substance from a bone-ligament-bone preparation. J Orthop Res 1983;1:22–29.
Woo SL-Y, Orlande CA, Gomez MS, Frank CB, Akeson WH: Tensile properties of medial collateral ligament as a dunction of age. J Orthop Res 1986;4:333–341.
Woodhead-Galloway J: Two theories of the structure of the collagen fibril, in Hukins DWL (ed): Connective Tissue Matrix. Deerfield Beach, Weinheim, 1984 133–160.
Yahia L-H, Dorwin G: Microscopical investigation of canine anterior cruciate ligament ant patellar tendon: collagen fascicle morphology and architecture. J Orthop Res 1989;7:243–251.
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Viidik, A. (1990). Structure and Function of Normal and Healing Tendons and Ligaments. In: Ratcliffe, A., Woo, S.LY., Mow, V.C. (eds) Biomechanics of Diarthrodial Joints. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3448-7_1
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