Electrical Activity of Mouse Carotid Body as Monitored by the Fluorescent Probe diS-C3-5: Effects of Different Agents
Voltage-sensitive dyes have allowed measurement of the potential difference across cell or organelles membranes, membrane vesicles, and cell complexes (1). This technique is based on the observation that changes in potential across membranes stained with certain dyes are accompanied by changes in the optical properties of the preparation; the data obtained by this method coincide with those obtained from the same cellular components with conventional methods (2). Some of these dyes respond to membrane potential changes in microseconds, whereas others, such as those used in this study, respond in seconds allowing the monitoring of slow electrical signals (1).
KeywordsCarotid Body Fluorescence Change Fluorescence Increase Glomus Cell Membrane Potential Change
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