Multicenter Validation Study of Real Time (B Mode) Ultrasound, Arteriography, and Pathology: V. Pathologic Evaluation of Endarteroctomy Specimens and of Perfusion Fixed Carotid Arteries

  • Eric A. Schenk
  • John Ricotta
  • M. Gene Bond
  • Thomas Aretz
  • Jean Angelo
  • Hong Y. Choi
  • Thomas Rinalski
  • Nancy Gustafson
  • Alan Berson
  • Fred A. Bryan
  • Barry Goldberg
  • James F. Toole
  • Daniel H. O’Leary

Abstract

During the implementation of an NIH sponsored contract program titled “Assessment of Ultrasonic B-Scan Imaging for Detection and Quantification of Atherosclerotic Lesions in Human Carotid Arteries”, 289 endarterectomy specimens became available for pathologic examination at five participating centers (Miami Heart Institute, Bowman Gray School of Medicine, New England Deaconess Medical Center, Jefferson Medical College, and University of Rochester Medical Center). These specimens were fixed in 10% neutral buffered formalin, decalcified, and cross-sectioned at 3 mm intervals. An overlay template was used to measure lumen diameters and near and far wall thickness in four planes.

Keywords

Formalin Shrinkage Luminal Decal Alan 

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References

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    Lusby RJ, Ferrell LD, Ehrenfeld WK, Stoney RJ, Wylie EJ (1982) Carotid plaque hemorrhage. Arch Surg 117:1479–1488.PubMedGoogle Scholar
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    Ricotta JJ, Schenk EA, Ekholm SE, Green RM, DeWeese JA (1986) Angiographic and pathologic correlates in carotid artery disease. Surgery 99:294–292.Google Scholar
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    Prendes JL, McKinney WM, Buonanno FS, Jones AM (1980) Anatomic variations of the carotid bifurcations affecting Doppler scan interpretation. J Clin Ultrasound 8:147–150.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag New York Inc. 1990

Authors and Affiliations

  • Eric A. Schenk
  • John Ricotta
  • M. Gene Bond
  • Thomas Aretz
  • Jean Angelo
  • Hong Y. Choi
  • Thomas Rinalski
  • Nancy Gustafson
  • Alan Berson
  • Fred A. Bryan
  • Barry Goldberg
  • James F. Toole
  • Daniel H. O’Leary

There are no affiliations available

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