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Congenital Hypoplastic Anemia (Diamond — Blackfan Anemia)

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Aplastic Anemia and Other Bone Marrow Failure Syndromes

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Abstract

Pure red blood cell (RBC) aplasia in children is a relatively common problem that usually represents a “pure erythroid abnormality” without other associated medical problems. This is in sharp contrast to the much rarer occurrences of RBC aplasia in adults, which often are associated with autoimmune disease, drugs, toxic exposures, malignancies, and, in a large fraction of patients, thymomas. The three major causes of pure red cell aplasia in children are Diamond — Blackfan anemia (DBA) transient erythroblastopenia of childhood (TEC), and acquired RBC hypoplasia associated with chronic hemolytic anemia. The major focus of this report is to summarize some of the current clinical problems related to Diamond — Blackfan anemia.

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Authors
  1. Bertil E. Glader
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Editors and Affiliations

  1. Department of Pediatrics, University of Wisconsin-Madison, Madison, Wisconsin, 53792, USA

    Nasrollah T. Shahidi

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© 1990 Springer-Verlag Inc.

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Glader, B.E. (1990). Congenital Hypoplastic Anemia (Diamond — Blackfan Anemia). In: Shahidi, N.T. (eds) Aplastic Anemia and Other Bone Marrow Failure Syndromes. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3254-4_15

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  • DOI: https://doi.org/10.1007/978-1-4612-3254-4_15

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7935-8

  • Online ISBN: 978-1-4612-3254-4

  • eBook Packages: Springer Book Archive

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