Abstract
Perinatal asphyxia occurs in 1% to 5% of all births and frequently results in a permanent neurological handicap.1 The extent of brain damage is probably related to the duration and degree of fetal hypoxia and ischemia and to resultant changes in cerebral metabolism. Following hypoxic-ischemic insults, cortical metabolism changes from aerobic to anaerobic glycolysis and has secondary changes in phosphorus-containing metabolites, lactate accumulation, and acidosis.2 These changes may represent the final common pathway of hypoxic cerebral damage that occurs after hypoxia or ischemia.3
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© 1990 Springer-Verlag New York Inc.
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Delivoria-Papadopoulos, M. (1990). Cerebral Phosphorus Magnetic Resonance Spectroscopy in Perinatal Distress. In: Pomerance, H.H., Bercu, B.B. (eds) Topics in Pediatrics. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3230-8_16
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DOI: https://doi.org/10.1007/978-1-4612-3230-8_16
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