Regulation of Inhibin and Activin Genes in the Rat Ovary

  • Joanna C. Dykema
  • Jason O. Rahal
  • Kelly E. Mayo
Part of the Serono Symposia USA book series (SERONOSYMP)


The gonadotropins, luteinizing hormone (LH) and follicle stimulating hormone (FSH), play major roles in regulating the mammalian reproductive cycle by influencing the gametogenic and steroidogenic functions of the gonads (1, 2). The simultaneous release of LH and FSH from anterior pituitary gonadotrophs is known to be positively regulated by the hypothalamic decapeptide GnRH (3,4). More recently, several gonadal peptides that specifically modulate FSH synthesis and secretion have been isolated and characterized. These include the inhibins, activins, and follistatin (5-12).


Corpus Luteum Estrous Cycle Follicular Fluid Atretic Follicle Preovulatory Follicle 
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Copyright information

© Springer-Verlag New York, Inc. 1991

Authors and Affiliations

  • Joanna C. Dykema
  • Jason O. Rahal
  • Kelly E. Mayo

There are no affiliations available

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