Flow Cytometric Analysis of Class I and II MHC Antigens on Ovine Luteal Cell Types
Secretion of progesterone by the corpus luteum (CL) is essential for the maintenance of early pregnancy in many species (1). The identification and characterization of two functionally and morphologically distinct types of steroidogenic luteal cells has provided several insights into the control of CL function (2). However, cells of the immune system may also play significant roles in the function and control of this ephemeral endocrine gland. Macrophages, lymphocytes, mast cells, monocytes, and eosinophils are found in CL of a variety of species (3). Their presence may indicate some role for the immune system in CL function.
KeywordsInterferon Prostaglandin Progesterone Nylon Azide
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- 8.Bottazzo GF, Pujol-Borrel R, Hanafusa T, Feldman R. Role of aberrant HLADR expression and antigen presentation in induction of endocrine autoimmunity. Lancet 1983;ii:1115–8.Google Scholar
- 9.Lobel BL, Levy E. Enzymatic correlates of development, secretory function and regression of follicles and corpora lutea in the bovine ovary, EL Formation, development, and involution of corpora lutea. Acta Endocrinol 1968; 59 (suppl 132): 35 – 51.Google Scholar
- 20.Fairchild DL, Pate JL. MHC antigen expression on bovine luteal cells varies during the estrous cycle. Biol Reprod 1989;40 (suppl l):236a.Google Scholar
- 22.Gogolin-Ewens KJ, Mackay CR, Mercer WR, Brandon MR. Sheep lymphocyte antigens (OLA), I. Major histocompatibility complex class I molecules. Immu-nology 1985; 56: 717 – 22.Google Scholar
- 24.Herman JR, Boullier JA, Roess DA, Parr RO, Barisas BG. Examination of cytokinetics and ploidy obtained from paraffin-embedded prostatic tissue. Cytometry, 1990.Google Scholar