Localization of Specific GnRH Receptors on Porcine Granulosa Cells and Mast Cells Within Ovarian Follicles
Follicular atresia is most likely a process involving several molecules and, perhaps, the ratios between them. There is evidence that the process may be influenced by a receptor capable of binding gonadotropin releasing hormone (GnRH). It has been reported that GnRH has direct effects on the rat ovary (1–4). Together, these and other reports support the conclusion that receptors capable of binding and mediating a response to GnRH exist in the rat ovary and that a GnRH-like molecule might play a role as an atretogenic factor in the ovary.
KeywordsMast Cell Luteinizing Hormone Granulosa Cell GnRH Agonist GnRH Antagonist
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- 6.Ledwitz-Rigby F, DeMent-Liebenow P. Direct action of gonadotropin releasing hormone and visualization of its receptors on porcine ovaries. In: Hirshfield A, ed. Growth factors and the ovary. New York: Serono Symposia, USA/Plenum Press, 1989: 279 – 83.Google Scholar
- 9.Adashi EY. Editorial: Cytokine-mediated regulation of ovarian function: Encounters of a third kind. Endocrinology 1989; 124: 2043.Google Scholar