Relaxin Secretion by the Primate Corpus Luteum During Simulated Early Pregnancy in Hyperstimulated Menstrual Cycles

  • J. S. Ottobre
  • R. L. Stouffer
  • C. A. VandeVoort
  • A. C. Ottobre
Part of the Serono Symposia USA book series (SERONOSYMP)


Peripheral concentrations of immunoreactive relaxin are generally undetectable during the nonfertile menstrual cycle in humans (1, 2) and rhesus monkeys (3, 4), but become measurable during pregnancy (2, 3, 5–7). The major source of relaxin in primates is the corpus luteum (CL)(5, 8–10). Chorionic gonadotropin (CG) induces relaxin secretion in nonpregnant primates (4,11,12) and thus appears to be a primary stimulus for such induction during early pregnancy. Relaxin is thought to play a role in uterine quiescence during pregnancy (13) and may be an important component for successful pregnancy maintenance.


Menstrual Cycle Rhesus Monkey Early Pregnancy Luteal Phase Corpus Luteum 
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Copyright information

© Springer-Verlag New York, Inc. 1991

Authors and Affiliations

  • J. S. Ottobre
  • R. L. Stouffer
  • C. A. VandeVoort
  • A. C. Ottobre

There are no affiliations available

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