Abstract
The evolution of multicellular organisms required communication between different cells to coordinate tissue function. These cell-cell interactions have become vital for the regulation of cellular function, growth, and differentiation.
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References
Skinner MK. Cell-cell interactions in the testis. Ann NY Acad Sci 1987; 513:158–171.
Bellve AR, Zheng W. Growth factors as autocrine and paracrine modulators of male gonadal functions. J Reprod Fertil 1989; 85:771–793.
Feig LA, Bellve AR, Erikson NH, Klagsbrun M. Sertoli cells contain a mitogenic peptide. PNAS 1980; 8:4774–4778.
Bellve AR, Fieg LA. Cellular proliferation in the mammalian testis: biology of the seminiferous growth factor. Recent Prog Horm Res 1984; 40:531–561.
Casella SJ, Smith EP, VanWyk JJ, et al. Isolation of rat testis cDNAs encoding an insulin-like growth factor I precursor. DNA 1988; 6:325–330.
Chaterlain PG, Naville D, Saez JM. Somatomedin-C/insulin-like growth factor-I-like material secreted by Sertoli cells in vitro: Characterization and regulation. Biochem Biophys Res Comm 1987; 146:1009–1017.
Vannelli BG, Barni T, Orlando C, Natali A, Serio M, Balboni GC. Insulin-like growth factor-I (IGF-I) and IGF-I receptor in human testis: An immunohistochemical study. Fertil Steril 1988; 49:666–669.
Benahmed M, Morera AH, Cauvin MC, DePeretti E. Somatomedic C/insulin-like growth factor I as a possible intratesticular regulator of Leydig cell activity. Mol Cell Endocrinol 1987; 50:69–77.
Skinner MK, Griswold MD. Multiplication stimulating activity (MSA) can substitute for insulin to stimulate the secretion of testicular transferrin by cultured Sertoli cells. Cell Biol Int Rep 1983; 7:441.
Borland K, Mita M, Oppenheimer CL, Blinderman LA, Massague J, Hall PF, Czech MP. The actions of insulin-like growth factors I and II on cultured Sertoli cells. Endocrinology 1984; 114:240.
Ueno N, Baird A, Esch F, Ling N, Guiellemin R. Isolation and partial characterization of a basic fibroblast growth factor from bovine testis. Mol Cell Endocrinol 1985; 49: 189–194.
Gospodarowicz D, Ferrara N. Fibroblast growth factor and the control of pituitary and gonad development and function. J Steroid Biochem 1989; 32:183–191.
Jaillard C, Chatelain PG, Saez JM. In vitro regulation of pig Sertoli cell growth and function: Effects of fibroblast growth factor and somatomedin C. Biol Reprod 1987: 665–674.
Smith EP, Hall SH, Monaco L, French FS, Wilson EM, Conti M. A rat Sertoli cell factor similar to bFGF increases c-fos messenger ribonucleic acid in culture Sertoli cells. Mol Endocrinol 1989; 3:954–961.
Ayer-LeLievre CA, Olson L, Ebendal T, Hallbook F, Persson HT. Nerve growth factor mRNA and protein in the testis and epididymis of mouse and rat. PNAS 1988; 85: 2628–2632.
Persson H, Ayer-Le Lievre CA, Soder O, Villar MJ, Metsis M, Olson L, Ritzen M, Hokfelt T. Expression of beta-nerve growth factor receptor mRNA in Sertoli cells downregulated by testosterone. Science 1990; 247:704–707.
Kahn SA, Soder O, Seyd V, Gustafsson K, Lindh M, Ritzen EM. The rat produces large amounts of an interleukin-I-like factor. Int J Androl 1987; 10:495–503.
Tsutsumi O, Kurachi H, Oka T. A physiological role of epidermal growth factor in male reproductive function. Science 1986; 233:975–977.
Holmes SD, Spotts G, Smith RG. Rat Sertoli cells secrete a growth factor that blocks epidermal growth factor (EGF) binding to its receptor. J Biol Chem 1986; 9:4076–4080.
Derynck R. Transforming growth factor-alpha. Cell 1988; 54:593–595.
Skinner MK, Takacs K, Coffey RJ Jr. TGF-alpha expression in the seminiferous tubule. Endocrinology 1989; 124:845–854.
Suarez-Quian CA, Dai M, Onida M, Kriss RM, Dym M. Epidermal growth factor receptor localization in the rat and monkey testes. Biol Reprod 1989; 41:921–932.
Morris PL, Vale WW, Cappel S, Bardin CW. Inhibin production by primary Sertoli cell-enriched cultures: Regulation by follicle stimulating hormones, androgens, and epidermal growth factor. Endocrinology 1988; 122:717–725.
Mallea LE, Machado AJ, Navaroli F, Rommerts FFG. Epidermal growth factor stimulates lactate production and inhibits aromatization in cultured Sertoli cells from immature rats. Int J Androl 1986; 9:201–208.
Roberts AB, Sporn MB. Transforming growth factor beta. Adv Cancer Res 1988; 51:107–145.
Benahmed M, Cochet C, Keramidas M, Chauvin MA, Morera AM. Evidence for a FSH dependent secretion of a receptor reactive transforming growth factor beta-like material by immature Sertoli cells in primary culture. Biochem Biophys Res Comm 1988; 153:1222–1231.
Skinner MK, Moses HL. Transforming growth factor beta gene expression and action in the seminiferous tubule. Mol Endocrinol 1989; 3:625–634.
Lin T, Blaisdell J, Haskell JF. Transforming growth factor beta inhibits Leydig steroidogenesis in primary cultures. Endocrinology 1987; 146:387–394.
Welsh TH Jr, Hseuh AJW. Mechanism of inhibitory action of epidermal growth factor on testicular androgen biosynthesis in vitro. Endocrinology 182; 110:1498–1506.
Fauser BCJM, Baird A, Hseuh AJW. Fibroblast growth factor inhibits luteinizing hormone-stimulated androgen production by cultured rat testicular cells. Endocrinology 1988; 123:2935–2941.
Skinner MK, Fetterolf PM, Anthony CT. Purification of a paracrine factor, PModS, produced by testicular peritubular cells that modulates Sertoli cell function. J Biol Chem 1987; 263:2884–2890.
Skinner MK, McLachlan RI, Bremner WJ. Stimulation of Sertoli inhibin secretion by the testicular paracrine factor PModS. Mol Cell Endocrinol 1989; 66:239–249.
Norton JN, Skinner MK. Regulation of Sertoli cell function and differentiation through the actions of a testicular paracrine factor, PModS. Endocrinology 1989; 124: 2711–2719.
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© 1991 Springer-Verlag New York, Inc.
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Mullaney, B.P., Skinner, M.K. (1991). Growth Factor Regulation of Testicular Function. In: Schomberg, D.W. (eds) Growth Factors in Reproduction. Serono Symposia, USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3162-2_4
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DOI: https://doi.org/10.1007/978-1-4612-3162-2_4
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