Skip to main content
SpringerLink
Log in

Toxicological-Hygienic Requirements for Study, Registration, and Regulations of Pesticides in the USSR

  • Chapter
Reviews of Environmental Contamination and Toxicology

Part of the book series: Reviews of Environmental Contamination and Toxicology ((RECT,volume 117))

Abstract

Pesticide toxicology is currently receiving a great deal of scientific and public attention throughout the world. Concerns include the high biological activity of pesticides, their steadily expanding application and distribution over vast areas in many countries, and their ability to invade the human body through foods of plant and animal origin, as well as through water and air.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Aldridge VN and Johnson MK (1972) Side-effect of organophosphorus compounds: neurotoxic action. WHO Bull. 144 N 1–2–3, pp 271–279.

    Google Scholar 

  • Alekseeva OG, Shumskaya NI (1970) Principles of standardization of chemical allergens. Meditsina, Moscow, pp 111–120.

    Google Scholar 

  • Antanovich EA (1972) Morphological alterations occurring in an organism from poisonings by DDT analogs—DDD and pertan. In: Hygiene and Toxicology of New Pesticides and Clinical Features of Poisonings. Medgiz, Moscow, pp 299–307.

    Google Scholar 

  • Archakov AI (1975) Microsomal oxidation. Meditsina, Moscow, 324 pp.

    Google Scholar 

  • Bakhishev GN (1986) Methyl-bromide. In: Handbook on Pesticides. Zdorovie, Kiev, pp 244–248.

    Google Scholar 

  • Belenky ML (1963) Elements of quantitative evaluation of pharmacologic effect. Medgiz, Leningrad, 149 pp.

    Google Scholar 

  • Bulletin of International Register of Potential Toxic Chemical Substances (1981). 4:31–33.

    Google Scholar 

  • Burkatskaya EN, Rudnichenko MF (1969) Study of allergic pesticide properties. In: Pesticide Use Hygiene, Toxicology and Clinical Features of Poisonings. Kiev, pp 166–172.

    Google Scholar 

  • Buslovich S Y (1986) Derivatives of chlorophenoxyacetic acid. In: Handbook on Pesticides. Urozhay, Kiev, pp 161–171.

    Google Scholar 

  • Chepinoga OP (1970) Pesticides investigated for blastomogenic, mutagenic, embryotoxic, gonadotoxic properties. In: Pesticide Use Hygiene, Toxicology and Clinical Features of Poisonings. Kiev, pp 30–39.

    Google Scholar 

  • Gar KA, Sazonova NA, Faleev YN (1959) Study on penetration and metabolism of two organophosphorus insecticides in an organism of warm-blooded animals. In: Hygiene, Toxicology and Clinical Features of New Insectofungicides. Medgiz, Moscow, pp 298–217.

    Google Scholar 

  • Giebel W, Lohs K, Wiedner GP (1973) Ãœber die kanzerogene hämatoxische und hepatox-ische Wirkung Pestizider organischen Phosphorverbindungen. Arch. f. Geschwulstforschung 4:311–328.

    Google Scholar 

  • Godovikov NN, Zeymal EV, Kabanchik MI, Mikhelson MY (1962) On dependence of distribution of organophosphorus compounds in an organism upon their chemical structure. In: Hygiene and Toxicology of New Pesticides and Clinical Features of Poisonings. Medgiz, Moscow, pp 203–205.

    Google Scholar 

  • Gofmekler VA, Khuriev BB (1970) On the problem of interrelation of air contamination with methyl-mercaptofos and pregnancy pathology in women under conditions of Uzbekistan. Transactions of the Conference on Hygienic Problems. Tashkent, pp 251–253.

    Google Scholar 

  • Goncharuk EI (1977) The main principles of hygienic standardization of chemicals in soil. In: Sanitary Soil Protection from contamination with Chemical Substances. Zdorovie, Kiev, pp 83–150.

    Google Scholar 

  • Kagan YS (1959) Actual problems in toxicology of organophosphorus insecticides. In: Hygiene, Toxicology, and Clinical Features of Insectofungicides. Medgiz, Moscow, pp 187–208.

    Google Scholar 

  • Kagan YS (1962) Toxicity of organophosphorus insecticides. In: Chemistry and application of organophosphorus compounds. Moscow Ac. of Science USSR, pp 458–462.

    Google Scholar 

  • Kagan YS (1963) Toxicology of organophosphorus insecticides and work hygiene of their use. Medgiz, Moscow, 327 pp.

    Google Scholar 

  • Kagan YS (1977) Toxicology of organophosphorus pesticides. Meditsina, Moscow, 296 pp.

    Google Scholar 

  • Kagan YS (1981) General toxicology of pesticides. Zdorovie, Kiev, 176 pp.

    Google Scholar 

  • Kagan YS (1985) Principles of pesticide toxicology, Centre of International Projects GKNT. International Register of Potential Toxic Chemicals, UNEP, Moscow, 176 pp.

    Google Scholar 

  • Kagan YS, Sasinovich LM (1973) Use of calculation methods for recommended tentative maximum allowable pesticide concentrations in the air of the working zone. Meditsine, Moscow, pp 31–40.

    Google Scholar 

  • Kagan YS, Stankevich VV (1964) Cumulation coefficient as quantitative criterion for evaluation of cumulative action of toxicant. In: Current Problems of Work Hygiene, Industrial Toxicology and Occupational Diseases in Petroleum and Petrochemical Industries, pp 48–49.

    Google Scholar 

  • Kagan YS, Kokshareva NV, Tkachenko N (1986). On early manifestations and mechanism of neurotoxic action of organophosphorus pesticides. Bull Exp Biol Med 9:310–312.

    Google Scholar 

  • Kagan YS, Krasovskiy GN, Shtabskiy BM (1986) Cumulative properties of chemicals, their study, and evaluation. In: Toxicology of Chemical Substances Contaminating the Environment. Centre of International Projects GKNT pp 104–134.

    Google Scholar 

  • Kagan YS, Sasinovich LM, Ovseenko GI (1976) A differentiated approach to setting calculated TSELs for individual pesticide classes. In: Application of Mathematical Methods for Evaluation of Pesticide Danger. Kiev, pp 78–81.

    Google Scholar 

  • Kagan YS, Fudel-Osipova SY, Khaykina BY, Kuzminskay UA, Kovtun SD (1969). On the problem of harmful effects of DDT and the mechanism of action. In: Residue Reviews 27. Springer-Verlag, New York, pp 43–79.

    Google Scholar 

  • Kagan YS, Ershova EA, Leonenko OB, Klisenko MA, Szminko PG, Zeinalova TA (1988) The role of monooxigenase system in metabolism and in mode of action of some pesticides. Vestnik of Academy of Med. Sei. of the USSR. Meditsina, Moscow 1:70–75.

    Google Scholar 

  • Kalayanova-Simeonova (1980). Pesticides. Meditsina, Moscow, 304 pp.

    Google Scholar 

  • Kasparov AA, Timofeevskaya LA, Litvinov NN, Trakhtenberg IM (1986) Chronic exposure to chemicals. In: Toxometry of Chemical Substances Contaminating the Environment. Centre of International Projects GKNT, pp 134–188.

    Google Scholar 

  • Kiriuschenkov AP (1978) Impact of harmful factors on skin. Moscow.

    Google Scholar 

  • Komorova LI (1976) Influence of organochlorine pesticides on the development of circulatory diseases. Problemi Gematologii i perelivaniya krovi 21,11:46–50.

    Google Scholar 

  • Krasovsky GN, Kagan YS, Szoldakova ZI, Voitenko GA (1986) Determination of lethal effects of toxic substances under different routes of intake. In: Toxometry of Chemical Substances Contaminating the Environment. Centre of International Projects GKNT, Moscow, pp 65–104.

    Google Scholar 

  • Kundiev YI (1962) Some methodical aspects of skin penetration study concerning organophosphorus insecticides. In: Hygiene and Toxicology of New Pesticides and Clinical Features of Poisonings. Medgiz, Moscow, pp 206–215.

    Google Scholar 

  • Kundiev YI (1975) Pesticide penetration through skin and prophylaxis of poisonings. Zdorovie, Kiev, 199 pp.

    Google Scholar 

  • Kundiev YI, Egorov YL, Shumskaya NI, Alekseeva OG, Roszkovskaya GP (1986) Skin-irritating, sensitizing, and resorptive action of substances. In: Toxometry of Chemical Substances Contaminating the Environment. Centre of International Projects GKNT, Moscow, pp 188–211.

    Google Scholar 

  • Kurinny AI, Pilinskaya MA (1976) Investigations of pesticides as environmental mutagens. Naukova Dumka, Kiev, 114 pp.

    Google Scholar 

  • Lakin KM, Krilov YF (1987) Biotransformation of medicinal substances. Meditsina, Moscow, pp.

    Google Scholar 

  • Lohs K, Dedeka W, Giebel W (1979) Studies on the alkylating properties of organophosphorus pesticides in mammals in vivo. In: 3-d Intern. Congr. of Pestic. Chemistry. Abstr. Book, Helsinky, p 328.

    Google Scholar 

  • Lukaneva AM (1976) Influence of low pesticide doses on the development of atherosclerosis in experiment. In: Pesticide Use Hygiene, Toxicology and Clinical Features of Poisonings, Moscow, II. 1:90–92.

    Google Scholar 

  • Lyublina EI, Minkina NA, Rilova ML (1971) Adaptation to industrial poisons as a phase of intoxication. Medgiz. Leningrad, 206 pp.

    Google Scholar 

  • Makhaeva GF, Maligin VV, Martinov IV (1987) Delayed neurotoxicity under exposure of organophosphorus pesticides. Agrochimiya 12:103–104.

    Google Scholar 

  • Makovskaya EI, Burkatskaya EN, Voitenko GA (1962) On DDT exposure on animal’s organism by inhalation. In: Hygiene and Toxicology of New Pesticides and Clinical Features of Poisonings, Medgiz, Moscow, pp 262–268.

    Google Scholar 

  • Malyuk VI (1966) On allergic diseases of chemical etiology. In: Hygiene and Toxicology of Pesticides and Clinical Features of Poisonings. Zdorovie, Kiev 4:42–53.

    Google Scholar 

  • Medved LI (1946) Toxicology of some organic mercuric compounds. State Medical Publishing House, Kiev, 110 pp.

    Google Scholar 

  • Medved LI (1976) Summary results and prospective goals of research in pesticide hygiene and toxicology. In: Pesticide Use Hygiene, Toxicology and Clinical Features of Poisonings. Moscow, II, 1:3–13.

    Google Scholar 

  • Medved LI, Spynu EI, Kagan YS (1968) Pesticides and public health problems. J Union Mendeleev Chem. Soc. 13, 3:263–271.

    CAS  Google Scholar 

  • Medved LI, Spynu EI, Antonovich EA, Vrachinsky KK, Kagan YS (1980) Condition and perspectives of complex hygienic standardization of pesticides in the environment. In: All-Union Constituent Conference on Toxicology. Theses of Reports, pp 14–17.

    Google Scholar 

  • Melnikov NN (1975) Chemistry and pesticide technology. Khimiya, Moscow, p 766.

    Google Scholar 

  • Melnikov NN (1987) Pesticides: Chemistry, technology, and application. Khimiya, Moscow, p 712.

    Google Scholar 

  • National Academy Press (1987). Regulating pesticides in food. Washington, D.C., p 272.

    Google Scholar 

  • Petrovskaya OG (1979) On blastomogenicity of chlorophos. In: The Newest Problems of Pesticide Use Hygiene. Theses of reports. Kiev, pp 164–165.

    Google Scholar 

  • Polchenko VY, Tkach LI, Gumenny VS, Sokolovsky NV, Baida LK (1976) Epidemiological aspects of the study of morbidity due to pesticide use in agriculture. In: Pesticide Use Hygiene, Toxicology, and Clinical Features of Poisonings. Moscow, 11:125–128.

    Google Scholar 

  • Popovich NA, Burkatskaya EN (1986) Derivatives of simmtriazines. In: Handbook of Pesticides. Uroszay, Kiev, pp 206–215.

    Google Scholar 

  • Prozorovsky VB (1962) Application of the least-squares method for probit-analysis of lethality curves. Framakologiyaitoxicologiya 1:115–120.

    Google Scholar 

  • Rodionov GA, Voronina BM (1973) Influence of chlorophos on development of hepato-pathology in experiment. Vrachebnoe Delo, 11:54–58.

    Google Scholar 

  • Rubenchik BL (1977) Biochemistry of carcinogenesis. Zdorovie, Kiev, 192 pp.

    Google Scholar 

  • Sanotsky IV (1970) (ed) Methods of determination of toxicity and danger of chemical substances (toxometry). Meditsina, Moscow.

    Google Scholar 

  • Sanotsky IV, Ulanova IP (1975) Criteria of harmfulness in hygiene and toxicology for hazard evaluation of chemical compounds. Meditsina, Moscow, 328 pp.

    Google Scholar 

  • Shabad LM (1966) To the question of hygienic standardization of carcinogenic substances. In: Gignia Sanit. 4. N 2, pp 18–23.

    Google Scholar 

  • Shabad LM (1978) Methods for determination and investigation of blastomogenicity of chemical substances. Moscow, 205 pp.

    Google Scholar 

  • Shkvatsabaya TK and Metelitsa VY (1971) In: Cardiology. Moscow N 2, pp 5–11.

    Google Scholar 

  • Shtabsky VM, Kagan YS (1974) Evaluation of cumulative properties of chemicals according to the index and standardization of coefficient of cumulation. Gigienai sanitariya 3:65–67.

    Google Scholar 

  • Shtenberg and Ribakova (1967) Influence of some pesticides in endocrine systems. In: Gigiena a Sanit. Moscow, N 1, pp 81–86.

    Google Scholar 

  • Shtenberg AI, Orlova NV, Torchinsky AM (1979) Effects of pesticides of different chemical structure on gonads and embryogenesis of experimental animals. Gigienai sanitariya

    Google Scholar 

  • Sidorov KK (1980) Substantiation system for the safety factor for establishing MAC of volatile substances in the air of the working zone. Gigiena truda iprofzabolevanija 6:17–19.

    Google Scholar 

  • Spynu EI (1962) Changes in the high nervous activity and functional state of the adrenal glands at exposure of low doses of insecticides of diene synthesis. In: Hygiene and Toxicology of New Pesticides and Clinical Features of Poisonings. Gosmedizdat, Moscow, pp 257–262.

    Google Scholar 

  • Spynu EI, Beim AM (1986) Ecologic-toxicologic methods of assessment of chemicals and their use in environmental hygiene. In: Toxicometry of Chemical Substances Contaminating the Environment. Centre of International Projects GKNT, pp 316–334.

    Google Scholar 

  • Spynu EI, Moloszanova EG (1981) Factors defining soil contamination with pesticides. Gigiena i sanitariya 5:16–18.

    Google Scholar 

  • Tkachenko H, Kagan YS, Kokshareva NV, Badaeva LN (1985) Delayed neurotoxic effects of a new fungicide-aphos. Farmakologiya i Toksikologiya 6:80–83.

    Google Scholar 

  • Trakhtenberg IM, Timofeevskaya LA, Kviatkovskaya IY (1987) Methods for studying chronic effects of chemical and biological pollutants. Zinatne, Riga, 142 pp.

    Google Scholar 

  • Turkevich NM, Samudzhan EM (1975) Hormones and carcinogenesis. Kiev, 168 pp.

    Google Scholar 

  • Turusov VS (1975) In: Vopzosi onkoligii. Leningrad, v 21, 12:127–135.

    Google Scholar 

  • Turusov VS (ed) (1987) Carcinogenic substances. Handbook: Transactions of International Agency of Cancer Research. Meditsina, Moscow, 334 pp.

    Google Scholar 

  • USSR Ministry of Health (1988) Methodical Instructions for Hygienic Evaluation of New Pesticides. VNHGINTOX.

    Google Scholar 

  • Vievskaya GA (1973) About neural-psychic disorders under protracted contact with organophosphorus pesticides. Vrachebnoye delo, 9:35–39.

    Google Scholar 

  • Voitenko GA, Kagan YS, Tomkiv VM, Fedorenko VI, Shtabsky BM (1984). On necessity of following up the ratio of oral and inhalative toxicity of substances while substantiating hygienic standards. Gigiena i sanitariya 6:13–16.

    Google Scholar 

  • Voronina VM (1971) Experimental data regarding the embryotoxic action of phtalophes. In: Pesticide Use Hygiene, Toxicology. Clinical Features of Poisoning. Kiev 9:254–257.

    Google Scholar 

  • World Health Organization (1988) The WHO recommended classification of pesticides hazard. Geneva, 39 pp.

    Google Scholar 

  • Zaugolnikov SD, Kochanov MM, Loit AO, Stavchinsky II (1978) Experimental methods for determination of toxicity and danger of chemical substances. Meditsina, Leningrad, pp.

    Google Scholar 

  • Zilber YD (1976) Neurotoxic action of poisons. In: Current Problems of Industrial Toxicology. Leningrad, pp 129–145.

    Google Scholar 

  • Zyuss P, Kintsel V, Scribner DD (1977) Cancer experiments and hypotheses, Mir, Moscow, 360 pp.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of General Toxicology and Experimental Pathology, All-Union Scientific Research Institute of Hygiene and Toxicology of Pesticides, Polymers and Plastics, Ministry of Health, Kiev, 252127, USSR

    Yu. S. Kagan (Chief)

Authors
  1. Yu. S. Kagan
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. College of Agriculture, University of Arizona, Tucson, Arizona, 85721, USA

    George W. Ware

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Springer-Verlag Inc. New York

About this chapter

Cite this chapter

Kagan, Y.S. (1991). Toxicological-Hygienic Requirements for Study, Registration, and Regulations of Pesticides in the USSR. In: Ware, G.W. (eds) Reviews of Environmental Contamination and Toxicology. Reviews of Environmental Contamination and Toxicology, vol 117. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3054-0_3

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-3054-0_3

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7777-4

  • Online ISBN: 978-1-4612-3054-0

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation