Abstract
Phencyclidine (PCP, angel dust, peace pill, cadillac, crystal joints, DOA) was synthesized in the 1960s by Parke–Davis Laboratories. The drug was originally intended for use as a surgical anesthetic, but it was found to produce violent postoperative psychosis (1,2). Because of its side effects, which included muscular rigidity as well as nightmares and frank delirium with frightening hallucinations and delusions, PCP was removed from the market for human use a few years after its introduction. It is still used as a tranquilizer in veterinary surgery.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Cohen S (1977). Angel dust. JAMA238:515–516.
Cohen S (1981). The Substance Abuse Problems. New York: Haworth.
Nicholi AM, Jr. (1984). Phencyclidine hydrochloride (PCP) use among college students: Subjective and clinical effects, toxicity, diagnosis and treatment. J Am Coll Health32:197–200.
Senay EC, Becker CE, Schnoll SH (1977). Emergency Treatment of the Drug–Abusing Patient: For Treatment Staff Physicians. Rosslyn, VA: National Drug Abuse Center.
Drug Enforcement Administration (1981). Drug Abuse Warning Network (DAWN) 1980 Annual Report, p. 130. Washington, DC: Drug Enforcement Administration.
Hinkely S, Greenwood J (1984). Emergency Room Visits in DAWN Projected to the Nation. Washington, DC: Drug Enforcement Administration.
Showalter CV, Thornton WE (1977). Clinical pharmacology of phencyclidine toxicity. Am J Psychiatry134:1234–1238.
Allen RM, Young SJ (1978). Phencyclidine-induced psychosis. Am J Psychiatry135: 1081–1084.
Fauman MA, Fauman BJ (1978). The psychiatric aspects of chronic phencyclidine (PCP) use: A study of phencyclidine users. In Phencyclidine (PCP) Abuse: An Appraisal, Petersen RC, Stillman, RC, eds., pp. 183–200. Rockville, MD: National Institute on Drug Abuse.
McAdams MT, ed. (1980). Phencyclidine Abuse Manual. Los Angeles: University of California Extension.
Kline NS, Lindenmayer JP (1981). Psychotropic Drugs: A Manual for Emergency Management of Overdosage, 2d Ed. Oradell, NJ: Medical Economics.
Done AK, Aronow R, Miceli JN (1978). The pharmacokinetics of phencyclidine in overdose and its treatment. In Phencyclidine (PCP) Abuse: An Appraisal, Petersen RC, Stillman RC, eds., pp. 210–217. Rockville, MD: National Institute on Drug Abuse.
Linder RL, Lerner SE, Burns RS (1981). PCP, the Devil’s Dust: Recognition, Management and Prevention of Phencyclidine Abuse. Belmont, CA: Wads worth.
Fauman MA, Fauman BJ (1979). Violence associated with phencyclidine abuse. Am J Psychiatry136:1584–1586.
Smith DE, Wesson DR, Buston ME, et al. (1978). The diagnosis and treatment of the PCP abuse syndrome. In Phencyclidine (PCP) Abuse: An Appraisal, Petersen RC, Stillman, RC, eds., pp. 218–228. Rockville, MD: National Institute on Drug Abuse.
Schuckit MA, Morrissey ER (1978). Propoxyphene and phencyclidine (PCP) use in adolescents. J Clin Psychiatry39:7–13.
DeAngelis GG, Goldstein E (1978). Long-term treatment of adolescent PCP abusers. In Phencyclidine (PCP) Abuse: An Appraisal, Petersen RC, Stillman, RC, eds., pp. 254–271. Rockville, MD: National Institute on Drug Abuse.
Miller NS, Gold MS (1987). The medical diagnosis and treatment of alcohol dependence. Med Times115 (9): 109–126.
Miller NS (1987). A primer of the treatment process for alcoholism and drug addiction. Psychiatry Lett5 (7): 30–37.
Author information
Authors and Affiliations
Rights and permissions
Copyright information
© 1991 Springer-Verlag New York
About this chapter
Cite this chapter
Miller, N.S. (1991). The Pharmacology of Phencyclidine. In: The Pharmacology of Alcohol and Drugs of Abuse and Addiction. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-3044-1_21
Download citation
DOI: https://doi.org/10.1007/978-1-4612-3044-1_21
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4612-7774-3
Online ISBN: 978-1-4612-3044-1
eBook Packages: Springer Book Archive