Abstract
Grass pollen is the major outdoor environmental factor provoking the immediate hypersensitive response of allergic disease in about one in five of the human population (see review by Howlett and Knox,1984). The symptoms are induced by the production of specific types of human defence molecules of the immune system, especially Immunoglubulin E (IgE). Allergens are environmental antigens which induce the formation of specific IgE, and bind specifically to IgE on the surface of epithelial mast cells. This triggers the mast cells to release the mediators of allergy.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Ansari AA, Shenbagamurthi, P, Marsh, DG. Complete amino acid sequence of a Lolium perenne (perennial rye grass) pollen allergen, Lol p II. J. Biol. Chem. 264: 11181 – 11185, 1989a.
Ansari AA, Shenbagamurthi, P, Marsh, DG. Complete primary structure of a Lolium perenne (perennial rye grass) pollen allergen, Lol p III: Comparison with known Lol p I and Lol p II sequences. Biochem. 28: 8665 – 8670, 1989b.
Ansari AA, Kikhara TK, Marsh DG. Immunochemical studies of Lolium perenne (Rye grass) pollen allergens, Lol p I, II, and III. J. Immunol. 139: 4034 – 4041, 1987.
Cottam GP., Moran DM, Standring R. Physicochemical and immunochemical characterisation of allergenic proteins from rye grass (Lolium perenne) pollen prepared by a rapid and efficient purification method. Biochem. J. 234: 305 – 310, 1986.
Esch RE, and Kiapper DG. Isolation and characterization of a major cross–reactive grass group I allergenic determinant. Mol. Immunol. 26: 557 – 561, 1989.
Gavel Y,and Von Heijne G. Sequence comparisons of transit peptides targeting proteins to chloroplasts. FEBS Letters. 261: 455 – 458, 1990.
Griffith IJ, Smith PM, Pollock J, Theerakulpisut P, Avjioglu A, Davies S, Hough T, Singh MB, Simpson RJ Ward LD, and Knox RB. Cloning and sequencing of Lol pi, the major allergenic protein of rye grass pollen. FEBS Letters 279: 210 – 215, 1991.
Howlett BJ, and Knox RB. Allergic interactions. Enc. Plant Physiol. 17: 656 – 673, 1984.
Johnson P,and Marsh DG. The isolation and characterisation of allergens from the pollen of rye grass (Lolium perenne). Euro. Polymer J. 1: 63 – 77, 1965.
Johnson P and Marsh DG. Allergens from common rye grass pollen, (Lolium perenne). Immunochem. 3: 101 – 110, 1966.
Jones RL, and Robinson DG. Protein secretion in plants. New Phytol. 111: 567 – 597, 1989.
Matthiesen F, and Lowenstein H. Group V allergens in grass pollens—1. Purification and characterisation of the group V allergen from Phleum pratense pollen, Phi p V. and II. Investigation of group V allergens in pollens from ten grasses. Clin. Ex. Allergy. 21: 297–307, 309 – 320, 1991.
Perez M, Ishioka GY, Walker LE, and Chestnut RW. cDNA cloning and immunological characterisation of the rye grass allergen Lol p I. J. Biol.Chem. 265: 16210 – 16215, 1990.
Silvanovich A, Astwood J, Zhang L, Olsen E, Kisil F, Sehon A, Mohapatra S, and Hill R. Nucleotide sequence analysis of three cDNA’s coding for Poa pIX isoallergens of Kentucky Bluegrass pollen. J. Biol. Chem. 266: 1204 – 1210, 1991.
Singh MB, Hough T, Theerakulpisut P, Avjioglu A, Davies S, Smith P, Taylor PE, Simpson RJ, Ward L, McCluskey J, Puy R, Knox RB. Isolation of cDNA encoding a newly identified major allergenic protein of rye grass pollen: Intracellular targeting to the amyloplast. Proc Nat Acad Sci, USA. 88: 1384 – 1388, 1991.
Spieksma FTM, Kramps JA, Linden AC. Van der, Nikkels BH, Plomp A, Koerten HK, Dijkman JH. Evidence of grass pollen allergenic activity in the smaller micronic atmospheric aerosol fraction. Clin. Exp. Allergy. 20: 273 – 280, 1990.
Stewart GA, Holt PG. Submicronic airborne allergens. Med J Aust. 143: 426 – 427, 1985.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1992 Springer-Verlag New York, Inc.
About this paper
Cite this paper
Knox, B. et al. (1992). Pollen Allergens: Molecular Cloning and Mechanism for Pollen-induced Asthma. In: Ottaviano, E., Gorla, M.S., Mulcahy, D.L., Mulcahy, G.B. (eds) Angiosperm Pollen and Ovules. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2958-2_2
Download citation
DOI: https://doi.org/10.1007/978-1-4612-2958-2_2
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4612-7733-0
Online ISBN: 978-1-4612-2958-2
eBook Packages: Springer Book Archive