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Effects of the 5-HT Uptake Inhibitor, Sertraline, on Ethanol, Water and Food Consumption

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Novel Pharmacological Interventions for Alcoholism
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Abstract

Several reports in the literature (Gill et al, 1985; Lucki et al, 1988; Gill et al, 1988a, b; Wong et al, 1988) have shown that 5HT uptake inhibitors decrease ethanol and food consumption in rats.

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References

  • Gill, K., Amit, Z. and Ogren, S.O. The effects of zimeldine on voluntary ethanol consumption: studies on the mechanism of action. Alcohol 2: 343–347 (1985).

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  • Gill, K., Amit, Z. and Koe, B.K. Treatment with sertraline, a new serotonin uptake inhibitor, reduces voluntary ethanol consumption in rats. Alcohol 5: 349–354 (1988a).

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  • Gill, K., Filion, Y., and Amit, Z. A further examination of the effects of sertraline on voluntary ethanol consumption. Alcohol 5: 355–358 (1988b).

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  • Lucki, I, Kreider, M.S. and Simansky, K.J. Reduction of feeding behavior by the serotonin uptake inhibitor sertraline. Psychopharmacol. 96: 289–295 (1988).

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  • Wong, D.T., Reid, L.R. and Threlkeld, P.G. Suppression of food intake in rats by fluoxetine: Comparison of enantiomers and effects of serotonin antagonists. Pharmacol. Biochem. Behav. 31: 475–479 (1988).

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© 1992 Springer-Verlag New York, Inc.

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Brands, B., Kaplan, H.L., Sellers, E.M. (1992). Effects of the 5-HT Uptake Inhibitor, Sertraline, on Ethanol, Water and Food Consumption. In: Naranjo, C.A., Sellers, E.M. (eds) Novel Pharmacological Interventions for Alcoholism. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2878-3_31

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  • DOI: https://doi.org/10.1007/978-1-4612-2878-3_31

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7705-7

  • Online ISBN: 978-1-4612-2878-3

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