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1,3-Butadiene: Toxicity and Carcinogenicity in Laboratory Animals and in Humans

  • Ronald L. Melnick
  • James Huff
Part of the Reviews of Environmental Contamination and Toxicology book series (RECT, volume 124)

Abstract

1,3-Butadiene, CH2=CH—CH=CH2 (CAS No. 106-99-0), is a colorless, noncorrosive gas having a boiling point of — 4.4°C and a vapor pressure of 1,900 mm Hg at 20°C (Kirshenbaum 1978). 1,3-Butadiene is a highly reactive material that can form the dimer, 4-vinyl-cyclohexene, and is flammable at atmospheric concentrations of 2% or higher. 1,3-Butadiene can form explosive peroxides in air, and therefore is shipped as a liquified gas under pressure with an inhibitor of peroxide formation, such ast-butyl catechol.

Keywords

Inhalation Exposure National Toxicology Program Carcinogenicity Study Thymic Lymphoma Epoxide Intermediate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer-Verlag New York Inc. 1992

Authors and Affiliations

  • Ronald L. Melnick
    • 1
  • James Huff
    • 1
  1. 1.National Institute of Environmental Health SciencesUSA

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