Skip to main content
SpringerLink
Log in

Moyamoya Disease

  • Chapter
Cerebrovascular Diseases in Children

Part of the book series: Principles of Pediatric Neurosurgery ((PRINCPEDIATR))

Abstract

At the fourteenth meeting of the Japanese Neurosurgical Society in 1955, Shimizu and Takeuchi reported a new disease entity designated as dysplasia of both internal carotid arteries1. This appears to be the first report of what we now refer to as moyamoya disease2. A succession of reports by a number of Japanese neurosurgeons3–6 of a similar disease followed, and the pathology of the disease was found to be characterized by the bilateral formation of abnormal netlike vessels at the base of the brain, associated with bilateral stenosis and/or occlusion of the arteries composing the circle of Willis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Shimizu K, Takeuchi K: Dysplasia of the bilateral internal carotid arteries. Oral presentation at the 14th meeting of the Japan Neurosurgical Society, Wakayama, 1955.

    Google Scholar 

  2. Suzuki J, Takaku A: Cerebrovascular moyamoya disease. Disease showing abnormal net-like vessels in base of brain. Arch Neurol 20: 288 – 299, 1969.

    PubMed  CAS  Google Scholar 

  3. Kudo T: Juvenile occlusion of the circle of Willis. Clin Neurology 5: 607 – 627, 1965.

    Google Scholar 

  4. Nishimoto A, Takeuchi S: Abnormal cerebrovascular network related to the internal carotid arteries. J Neurosurg 29: 255 – 260, 1968.

    Article  PubMed  CAS  Google Scholar 

  5. Suzuki J, Takaku A, Asahi M, Kowada M: Disease showing the“Fibrille”-like vessels at the base of brain. No To Shinkei 17: 767 – 776, 1965.

    PubMed  CAS  Google Scholar 

  6. TakeuchiK, Shimizu K: Hypoplasia of the bilateral internal carotid arteries. No To Shinkei 9: 37 – 43, 1957.

    Google Scholar 

  7. Kudo T: Spontaneous occlusion of the circle of Wills. A disease apparently confined to Japanese. Neurology 18: 485 – 496, 1968.

    PubMed  CAS  Google Scholar 

  8. Weidner W, Hanafee W, Markham CH: Intracranial collateral circulation via leptomeningeal and rate mirabile anastomosis. Neurology 15: 39 – 48, 1965.

    PubMed  CAS  Google Scholar 

  9. Krayenbuhl HA: The moyamoya syndrome and neurosurgeon. Surg Neurol 4: 353 – 360, 1975.

    PubMed  CAS  Google Scholar 

  10. Taveras JM: Multiple progressive intracranial occlusions: A syndrome of children and young adults. AJR 106: 235 – 268, 1969.

    CAS  Google Scholar 

  11. Nishimoto A: Moyamoya disease. Neurol Med Chir 19: 221 – 228, 1979.

    Article  CAS  Google Scholar 

  12. Suzuki J, Kodama N: Moyamoya disease. A review. Stroke 14: 104 – 109, 1983.

    Article  PubMed  CAS  Google Scholar 

  13. Adams HP Jr, Kassell NF, Wisoff HS, Drake CG: Intracranial saccular aneurysm and moyamoya disease. Stroke 10: 174 – 179, 1979.

    Article  PubMed  Google Scholar 

  14. Nagamine Y, Takahashi S, Sonobe M: Multiple intracranial aneurysms associated with moyamoya disease. J Neurosurg 54: 673 – 676, 1981.

    Article  PubMed  CAS  Google Scholar 

  15. Yamashita M, Oka K, Tanaka K: Histopathology of the brain Ovascular network in moyamoya disease. Stroke 14: 50 – 58, 1983.

    Article  PubMed  CAS  Google Scholar 

  16. Fukuyama Y: Clinical and cerebral angiographic evolutions of idiopathic progress occlusive disease of the circle of Willis (“moyamoya” disease) in children. Brain Dev 7: 21 – 37, 1985.

    PubMed  CAS  Google Scholar 

  17. Kitahara T, Ariga N, Yamaura A, Makino H, Maki Y: Familial occurrence of moyamoya disease: Report of three Japanese families. J Neurol Neurosurg Psychiatry, 42: 208 – 214, 1979.

    Article  PubMed  CAS  Google Scholar 

  18. Kitahara T, Okumura K, Semba A, Yamaura A, Makino H: Genetic and immunologic analysis on moyamoya. J Neurol Neurosurg Psychiatry 45: 1048 – 1053, 1982.

    Article  PubMed  CAS  Google Scholar 

  19. Nishimoto A, Takeuchi S: Moyamoya Disease. In: Vinken PJ, Bruyn GW (eds.) Handbook of Clinical Neurology. American Elsevier Publishing Company, New York, 1972, pp 352 – 382.

    Google Scholar 

  20. Miyamoto S, Kikuchi H, Karasawa J, Nagata I, Ikota T, Takeuchi S: Study of the posterior circulation in moyamoya disease. Clinical and Neuroradiological evaluation. J Neurosurg 61: 1032 – 1037, 1984.

    Article  PubMed  CAS  Google Scholar 

  21. Sato S, Shibuya H, Matsushima Y, Suzuki S: Analysis of the angiographic findings in cases of childhood moyamoya disease. Neuroradiology 30: 111 – 119, 1988.

    Article  Google Scholar 

  22. Kodama N, Aoki Y, Hiraga H, Wada T, Suzuki J: Electroencephalographic findings in children with moyamoya disease. Arch Neurol 36: 16 – 19, 1979.

    PubMed  CAS  Google Scholar 

  23. Takahashi A, Fujiwara S, Suzuki J: Cerebral angiography following hyperventilation in moyamoya disease. In reference to the “re-build up” phenomenon on EEG. No Shinkei Geka 13:255–264, 1985.

    Google Scholar 

  24. Ohyama H, Niizuma H, Fujiwara S, Suzuki J: EEG findings in moyamoya disease in children with special reference to the genesis of “re-build” up. No Shinkei Geka 13: 727 – 733, 1985.

    PubMed  CAS  Google Scholar 

  25. Kameyama M, Shirane R, Tsurumi Y, Takahashi A, Fujiwara S, Suzuki J, Ito M, Ido T: Evaluation of cerebral blood flow and metabolism in childhood moyamoya disease. An investigation into “re-build-up” on EEG by positron CT. Childs Nerv Syst 2: 130 – 133, 1986.

    Article  PubMed  CAS  Google Scholar 

  26. Sato H, Sato N, Tamaki N, Matsumoto S: Chronic low-perfusion state in children with moyamoya disease following revascularization. Childs Nerv Syst 6: 166 – 171, 1990.

    Article  PubMed  CAS  Google Scholar 

  27. Takahashi M, Miyauchi T, Kowada M: Computed tomography of moyamoya disease: Demonstration of occluded arteries and collateral vessels as important diagnostic signs. Radiology 134: 671 – 676, 1980.

    PubMed  CAS  Google Scholar 

  28. Takeuchi S, Kobayashi K, Tsuchida T, Imamura H, Tanaka R, Ito J: Computed tomography in moyamoya disease. J Comput Assist Tomogr 6: 24 – 32, 1982.

    Article  PubMed  CAS  Google Scholar 

  29. Bruno A, Yuh WTC, Biller J, et al: Magnetic resonance imaging in young adults with cerebral infarction due to moyamoya. Arch Neurol 45: 303 – 306, 1988.

    PubMed  CAS  Google Scholar 

  30. Fujisawa I, Asato R, Mishimura K, Kogashi K, Itoh K, et al: Moyamoya disease. MR imaging. Radiology 164: 103 – 105, 1987.

    PubMed  CAS  Google Scholar 

  31. Fujita K, Shirakuni T, Kojima N, Matsumoto S: Magnetic resonance imaging. No Shinkei Geka 14: 324 – 330, 1986.

    PubMed  CAS  Google Scholar 

  32. Rolak LA, Rokey R: Magnetic resonance imaging in moyamoya disease. J Child Neurol 1: 67 – 70, 1986.

    Article  PubMed  CAS  Google Scholar 

  33. Ogawa A, Nakamura N, Sakurai Y, Kayama T, Wada T, Suzuki J: Cerebral blood flow in moyamoya disease. No To Shinkei 39: 199 – 203, 1987.

    PubMed  CAS  Google Scholar 

  34. Takeuchi S, Tanaka R, Ishii R, Tsuchida T, Kobayashi K, Arai H: Cerebral hemodynamics in patients with moyamoya disease. A study of regional cerebral blood flow by the 133Xe inhalation method. Surg-Neurol 23: 468 – 474, 1985.

    Article  PubMed  CAS  Google Scholar 

  35. Nakao K, Yamada K, Hayakawa T, Tagawa T, Yoshimine T, Ushio Y, Mogami H: Intraoperative measurement of cortical blood flow and its C02 response in childhood moyamoya disease. Neurosurgery 21: 509 – 14, 1987.

    Article  PubMed  CAS  Google Scholar 

  36. Tatemichi TK, Prohovink I, Mohr JP, Correll JW, Quest DO, Jarvis I: Reduced hypercapnic vasoreactivity in moyamoya disease. Neurology 38: 1575 – 1581, 1988.

    PubMed  CAS  Google Scholar 

  37. Taki W, Yonekawa Y, Kobayashi A, Ishikawa M, Kikuchi H, Nishizawa S, Senda M, Yonekawa Y, Fukuyama H, Harada K, et al: Cerebral circulation and oxygen metabolism in moyamoya disease of ischemic type in children. Childs Nerv Syst 4: 259 – 262, 1988.

    PubMed  CAS  Google Scholar 

  38. Tomura N, Kanno I, Shishido F, Higano S, Fujita H, Inugami A, Tabata K, Uemura K, Sayama I, Yasui N: Vascular responses in cerebrovascular “Moyamoya” disease evaluated by positron emission tomography. No To Shinkei 41: 895 – 904, 1989.

    PubMed  CAS  Google Scholar 

  39. Kuwabara Y, Ichiya Y, Otsuka M, Tahara T, Gunasekera R, Hasuo K, Masuda K, Matsushima T, Fukui M: Cerebral hemodynamic change in the child and the adult with moyamoya disease. Stroke 21: 272 – 277, 1990.

    Article  PubMed  CAS  Google Scholar 

  40. Nishimoto A, Takeuchi S: Moyamoya Disease. In: Vinken PJ, Bruyn GW (eds.) Handbook of Clinical Neurology, American Elsevier Publishing Company, New York, 1972, pp 352 – 383.

    Google Scholar 

  41. Ohtoh T, Iwasaki Y, Namiki T, Nakamura K, Sakurai Y, Ogawa A, Wada T: Hemodynamic characteristics of the vertebrobasilar system in moyamoya disease. A histometric study. Hum- Pathol 19: 465 – 470, 1988.

    Article  PubMed  CAS  Google Scholar 

  42. Oka K, Yamashita M, Sadoshima S, Tanaka K: Cerebral hemorrhage in moyamoya disease at autopsy. Virchows Arch Pathol Anat 392: 247 – 261, 1981.

    PubMed  CAS  Google Scholar 

  43. Gomez CR, Hogan PA: Unilateral Moyamoya disease in an adult. A case history. Angiology 38: 342 – 346, 1987.

    Article  PubMed  CAS  Google Scholar 

  44. Matsushima T, Fukui M, Fujii K, Fujiwara S, Nagata S, Kitamura K, Kuwabara Y: Two pediatric cases with occlusions of the ipsilateral internal carotid and posterior cerebral arteries associated with moyamoya vessels. “Unilateral” moyamoya disease. Surg Neurol 33: 276 – 280, 1990.

    Article  PubMed  CAS  Google Scholar 

  45. Matsushima T, Take S, Fujii K, Fukui M, Hasuo K, Kuwabara Y, Kitamura K: A case of moyamoya disease with progressive involvement from unilateral to bilateral. Surg Neurol 30: 471 – 475, 1988.

    Article  PubMed  CAS  Google Scholar 

  46. Takeuchi K: Moyamoya syndrome and Moyamoya disease. No To Shinkei 30: 1183 – 1191, 1978.

    PubMed  CAS  Google Scholar 

  47. Wilms G, Marchal G, Van Fraeyenhoven L, Demaerel P, Casaer P, Van Elderen S, Baert AL: Unilateral moyamoya disease. MRI findings. Neuroradiology 31: 442, 1989.

    Article  PubMed  CAS  Google Scholar 

  48. Ishikawa M, Handa H, Mori K, Matsuda I: Moyamoya vessels on the tumor in the seller region. Arch Jap Chir 48: 639 – 644, 1979.

    CAS  Google Scholar 

  49. Tsuji N, Kuriyama T, Iwamoto M, Shizuki K: Moyamoya disease associated with craniopharyngioma. Surg Neurol 21: 588 – 592, 1984.

    Article  PubMed  CAS  Google Scholar 

  50. Hilar SK, Solomon GE, Gold AP, Carter S: Primary cerebral arterial occlusive disease in children. Part II. Neurocutaneous syndromes. Radiology 99: 87 – 94, 1974.

    Google Scholar 

  51. Yashon D, Johnson AB, Jane JA: Bilateral internal carotid artery occlusion secondary to closed head injuries. J Neurol Neurosurg Psychiatry 27: 547 – 552, 1964.

    Article  PubMed  CAS  Google Scholar 

  52. Pilz P: Fibromuscular dysplasia and multiple dissecting aneurysms of intracranial arteries. A further cause of moyamoya syndrome. Stroke 7: 393 – 398, 1976.

    Article  PubMed  CAS  Google Scholar 

  53. Bingham WFB, Beguin EA, Ramirez-Lassepas: Moyamoya disease in pregnancy. Wis Med J 79: 21 – 25, 1980.

    PubMed  CAS  Google Scholar 

  54. Rajakulasingam K, Cerullo LJ, Raimondi AJ: Childhood moyamoya syndrome. Childs Brain 5: 467 – 475, 1979.

    PubMed  CAS  Google Scholar 

  55. Kurokawa T, Tomita S, Ueda K, Narazaki O, Hanai T, Hasuo K, Matsushima T, Kitamura K: Prognosis of occlusive disease of the circle of Willis (moyamoya disease) in children. Pediatr Neurol 1: 274 – 277, 1985.

    Article  PubMed  CAS  Google Scholar 

  56. Tsubokawa T, Kikuchi M, Asano S, Itoh H, Urabe M: Surgical treatment for intracranial thrombosis. Case report of “Durapexia”. Neurol Med Chir 6: 428 – 429, 1964.

    Article  Google Scholar 

  57. Suzuki J, Takaku A, Kodama N, Sato S: An attempt to treat cerebrovascular moyamoya disease in children. Childs Brain. 1: 193 – 206, 1975.

    PubMed  CAS  Google Scholar 

  58. Karasawa J, Kikuchi H, Furuse S: A surgical treatment of “moyamoya” disease “encephalo-myo-synangiosis”. Neurol Med Chir 17: 30 – 37, 1977.

    Google Scholar 

  59. Karasawa J, Kikuchi H, Furuse S, Kawamura J, Sasaki T: Treatment of moyamoya disease with STA-MCA anastomosis. J Neurosurg 49: 679 – 688, 1978.

    Article  PubMed  CAS  Google Scholar 

  60. Takeuchi S, Kikuchi H, Karasawa J, Yamagata S, Nagata I: Regional cortical flow during extra-intracranial bypass surgery in young patients with moyamoya disease. Neuro Med Chir 29: 10 – 14, 1989.

    Article  CAS  Google Scholar 

  61. Amine ARC, Moody RA, Meeks W: Bilateral temporal middle cerebral artery anastomosis for moyamoya syndrome. Surg Neurol 8: 3 – 6, 1977.

    PubMed  CAS  Google Scholar 

  62. Karasawa J, Kikuchi H, Kawamura J, Sakaki T: Intracranial transplantation of the omentum for cerebrovascular moyamoya disease. A two year follow-up study. Surg Neurol 14: 444 – 449, 1980.

    PubMed  CAS  Google Scholar 

  63. Matsushima Y, Fukai N, Tanaka K, Tsuruoka S, Inaba Y, Aoyagi M, Ohno K: A new surgical treatment of moyamoya disease in children. A preliminary report. Surg Neurol 15: 313 – 320, 1981.

    Article  PubMed  CAS  Google Scholar 

  64. Ichikawa A, Tanaka R, Takeuchi S, Koike T, Ishii R: Reconstructive vascular surgery in children with moyamoya disease. Neurol Med Chir 29: 106 – 112, 1989.

    Article  CAS  Google Scholar 

  65. Nakagawa Y, Gotoh H, Shimoyama M, Ohtsuka K, Mabuchi S, Sawamura Y, Abe H, Tsuru M: Reconstructive operation for moyamoya disease. Surgical indication for the hemorrhagic type, and preferable operative methods. Neurol Med Chir 23: 464 – 470, 1983.

    Article  CAS  Google Scholar 

  66. Matsushima Y, Inaha Y: Moyamoya disease in children and its surgical treatment. The introduction of a new surgical procedure and its follow up angiograms. Childs Brain 11: 155 – 170, 1984.

    PubMed  CAS  Google Scholar 

  67. Olds MV, Griebel RW, Hoffman HJ, Craven M, Chuang S, Schutz H: The surgical treatment of childhood moyamoya disease. J Neurosurg 66: 675 – 680, 1987.

    Article  PubMed  CAS  Google Scholar 

  68. Matsushima T, Fujiwara S, Nagata S, Fujii K, Fukui M, Kitamura K, Hasuo K: Surgical treatment for paediatric patients with moyamoya disease by indirect revascularization procedures (EDAS, EMS, EMAS). Acta Neurochir 98: 135 – 140, 1989.

    Article  CAS  Google Scholar 

  69. Fujita K, Tamaki N, Matsumoto S: Surgical treatment of moyamoya disease in children: which is more effective procedure. DEAS or EMS? Childs Nerv Syst 2: 134 – 138, 1986.

    Article  PubMed  CAS  Google Scholar 

  70. Eller TW, Pasternak JF: Revascularization for moyamoya disease. Five-year follow-up. Surg Neurol 28: 463 – 467, 1987.

    Article  PubMed  CAS  Google Scholar 

  71. Matsushima Y, Inaba Y: The specificity of the collaterals to the brain through the study and treatment of moyamoya disease. Stroke 17: 117 – 122, 1986.

    Article  PubMed  CAS  Google Scholar 

  72. Shimoji T, Sato K, Ito M: Cerebral revascularization for moyamoya disease. Usefulness of EDAS Nervous System in Children. 15: 161 – 168, 1990.

    Google Scholar 

  73. Miyamoto S, Kikuchi H, Karasawa J, Nagata I, Yamazoe N, Akiyama Y: Pitfalls in the surgical treatment of moyamoya disease Operative techniques for refractory cases. J Neurosurg 68: 537 – 543, 1973.

    Google Scholar 

  74. Ishii R, Takeuchi S, Kobayashi K, Tanaka R: Intelligence in children with moyamoya disease. Evaluation after surgical treatments with special reference to changes in cerebral blood flow. Stroke 15: 873 – 877, 1984.

    Article  PubMed  CAS  Google Scholar 

  75. Takeuchi S, Tsuchida T, Kobayashi K, Fukuda M, Ishii R, Tanaka R, Ito J: Treatment of moyamoya disease by temporal muscle graft encephalo myo synangiosis. Childs Brain 10: 1 – 15, 1983.

    PubMed  CAS  Google Scholar 

  76. Suzuki R, Matsushima Y, Takada Y, Nariai T, Wakabayashi S, Tone O: Changes in cerebral hemodynamics following encephalo-duro-arterio-synangiosis (EDAS). In young patients with moyamoya disease. Surg Neurol 31:343–349, 1989.

    Google Scholar 

  77. Moritake K, Handa H, Yonekawa Y, Taki W, Okuno T: Follow-up study on the relationship between age at onset of illness and outcome in patients with moyamoya disease. No Shinkei Geka 14: 957 – 963, 1986.

    PubMed  CAS  Google Scholar 

  78. Bingham RM, Wilkinson DJ: Anaesthetic management in moyamoya disease. Anaesthesia 40: 1198–1202 (68), 1985.

    Google Scholar 

Download references

Authors
  1. Kiyoshi Sato
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Takeyoshi Shimoji
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Northwestern University Medical Schoool, Chigago, Illinois, USA

    Anthony J. Raimondi M.D. (Professor of Surgery (Neaurosurgery) (Professor of Surgery (Neaurosurgery)

  2. Hôpital des Enfantes de la Timone, Rue Sainte Pierre, 13005, Marseille, France

    Maurice Choux M.D.

  3. Instituto di Neuochirurgia, Università Cattolica del Sacre Cuore, Largo Gemelli 8, 00168, Rome, Italy

    Concezio Di Rocco M.D.

Rights and permissions

Reprints and permissions

Copyright information

© 1992 Springer-Verlag New York Inc.

About this chapter

Cite this chapter

Sato, K., Shimoji, T. (1992). Moyamoya Disease. In: Raimondi, A.J., Choux, M., Di Rocco, C. (eds) Cerebrovascular Diseases in Children. Principles of Pediatric Neurosurgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2800-4_17

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-2800-4_17

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7676-0

  • Online ISBN: 978-1-4612-2800-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation