Abstract
The ectocervix and vagina are lined by stratified squamous epithelium, which can be divided into several different layers during the reproductive phase of life. From the deepest layer, they are: 1) the basal layer (stratum cylindricum), 2) the parabasal zone (deep spinous layer), 3) the intermediate zone (superficial spinous layer), and 4) the superficial layer (stratum corneum) (Fig. 18.1). The upper two layers, the intermediate and superficial layers, change in thickness under the influence of ovarian hormones. Because of its sensitivity to estrogen and progesterone, a scraping of the lateral wall of the vagina provides a specimen suitable for evaluating the hormonal state. Hormonal evaluation of a smear is based on the proportion of the various types of squamous cells.
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References
Kim K, et al. The changing trends of uterine cancer and cytology: A study of morbidity and mortality trends over a twenty year period. Cancer. 1978;42:2439.
Patten SF. Benign Proliferative Reactions of the Uterine Cervix. In: Compendium on Diagnostic Cytology. 6th ed. 1988.
Weid GL. Proceedings of the First International Congress on Exfoliative Cytology, 1st ed. Philadelphia: JB Lippincott, 1961.
Richart RM. Cervical Intraepithelial Neoplasia. Pathology Annual. Norwalk, Conn: Appleton-Century-Crofts, pp 301–328.
Fu YS, Reagan JW, Richart RM. Definitions of precursors. Gynecol Oncol. 1981;12:5220.
Fu YS, Reagan JW, Richart RM. Precursors of cervical cancer. Cancer Surv 1983;2:359.
Richart RM, Barron BA. A follow-up study of patients with cervical dysplasia. Am J Obstet Gynecol. 1969;105:386.
Townsend DE, Richart RM. Cryotherapy and carbon dioxide laser management of cervical intraepithelial neoplasia. A controlled comparison. Obstet Gynecol. 1983;61:75.
Meisels A, et al. Human papilloma virus (HPV), venereal infections and gynecologic cancer. Path Annu. 1983;18(2):277.
Roy M, Meisels A, Fortier M, et al. Vaginal condylomata: A human papilloma virus infection. Clin Obstet Gynecol. 1981;24:261.
Koss LG. Precancerous lesions of the epithelia of the uterine cervix. In: Compendium on Diagnostic Cytology. 6th ed. 1988;96–104.
The 1988 Bethesda System for Reporting Cervical/Vaginal Cytological Diagnosis. National Cancer Institute Workshop. JAMA. 1988;262:931–934.
Barron BA, Cahill MC, Richart RM. A statistical model of the natural history of cervical carcinoma. II. Estimates of the transition time from dysplasia to carcinoma in situ. J Natl Cancer Inst. 1978;45:1025.
Barron BA, Cahill MC, Richart RM. A statistical model of the natural history of cervical carcinoma in situ. Gynecol Oncol. 1978;6:196.
Old JW, Wielenga G, von Haam E. Squamous carcinoma in situ of the uterine cervix. I. Classification and histogenesis. Cancer. 1965;18:1596.
Fu YS, Reagan JW Pathology of the uterine cervix, vagina and vulva. In: Major Problems in Pathology, Vol. 21. Philadelphia: WB Saunders Co; 1989;248–251.
Fu YS, Berek JS. Minimal cervical cancer: Definition and histology. In: Minimal Neoplasia—Diagnosis and Therapy. Recent Results in Cancer Research, Vol 106. Berlin: Springer-Verlag; 1988;47–56.
Silverberg E, Dubera JA. Cancer statistics. CA. 1989;39:3–20.
Broders AC. Carcinoma: Grading and practical application. Arch Pathol. 1926;2:376–381.
Reagan JW, Fu YS. Histologic types and prognosis of cancers of the uterine cervix. Int J Radiat Oncol Biol Phys. 1979;5:1015.
Martzloff KH. Carcinoma of the cervix uteri. A pathological clinical study with particular reference to the relative malignancy of the neoplastic process as indicated by the predominant type cancer cell. Bull Johns Hopkins Hosp. 1923;34:141.
Wentz WB, Reagan JW. Survival in cervical cancer with respect to cell type. Cancer. 1959;12:384.
Reagan JW, Fu YS. Histologic types and prognosis of cancers of the uterine cervix. Int J Radiat Oncol Biol Phys. 1979;5:1019.
Fu YS, Reagan JW. Pathology of the Uterine Cervix, Vagina, and Vulva. Philadelphia: WS Saunders Co; 1989;289–326.
Herbst AL, Robboy SL, Scully RE, et al. Clear cell adenocarcinoma of the vagina and cervix in girls: An analysis of 170 registry cases. Am J Obstet Gynecol. 1974;119:713.
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© 1992 Springer-Verlag New York, Inc.
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Kim, K., Naylor, B. (1992). The Uterine Cervix. In: Practical Guide to Surgical Pathology with Cytologic Correlation. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2764-9_18
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DOI: https://doi.org/10.1007/978-1-4612-2764-9_18
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