Expression and Binding of Transforming Growth Factor ßs in the Mouse Embryo and Uterus During the Periimplantation Period

  • S. K. Dey
  • S. K. Das
  • B. C. Paria
  • K. C. Flanders
  • G. K. Andrews
Conference paper
Part of the Serono Symposia, USA book series (SERONOSYMP)


The implantation process involves complex interactions between embryonic and uterine cells. The major events of the implantation process are (i) synchronized development of the preimplantation embryo into a blastocyst and establishment of the receptive uterus (1); (ii) escape of the embryo from immunological responses of the mother (2); (iii) increased endometrial capillary permeability at the site of the blastocyst apposition (1); (iv) localized decidualization of the endometrial stroma following blastocyst attachment (1,3); and (v) controlled uterine invasion by trophoblasts (4). These events are a conglomerate of temporally and spatially regulated proliferation, differentiation, migration, and remodeling of heterogeneous cell types of both the embryonic and uterine tissues.


Transform Growth Factor Preimplantation Embryo Mouse Uterus Preimplantation Mouse Embryo Preimplantation Embryo Development 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer-Verlag New York, Inc 1993

Authors and Affiliations

  • S. K. Dey
  • S. K. Das
  • B. C. Paria
  • K. C. Flanders
  • G. K. Andrews

There are no affiliations available

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