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In Utero Diagnosis of Congenital Infection

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Viral Diseases in Pregnancy

Abstract

Toxoplasma, rubella, cytomegalovirus, and herpes simplex virus, known by the acronym TORCH, constitute a heterogeneous group of mostly viral agents having the potential to cause in utero or peripartum illness in the fetus and newborn.1,2 The classic “TORCH fetus” suggests a constellation of problems arising from multiorgan infection such as intrauterine growth retardation, hydrocephalus, chorioretinitis, hepatosplenomegaly, or bone marrow suppression. The spectrum of pathology is quite broad (Table 3-1).

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Isada, N.B., Berry, S.M. (1994). In Utero Diagnosis of Congenital Infection. In: Gonik, B. (eds) Viral Diseases in Pregnancy. Clinical Perspectives in Obstetrics and Gynecology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2640-6_3

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