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Parvovirus

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Book cover Viral Diseases in Pregnancy

Part of the book series: Clinical Perspectives in Obstetrics and Gynecology ((CPOG))

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Abstract

Human parvovirus B19 was discovered by Cossart et al in 1975 while they were evaluating a false-positive result in a counterimmu-noelectrophoresis screening test for hepatitis B antigen1; however, it was not until 1981 that another chance discovery led to the first link between parvovirus B19 and human disease. It was the discovery of viremia in two children attending a clinic in London that led to the description of six cases of aplastic crisis associated with parvovirus B19 infection in children with sickle cell anemia.2 In 1983, erythema infectiosum, or fifth disease, a common childhood exanthem, was shown to be caused by parvovirus B19 infection.3 In 1985, parvovirus B19 infection was linked to acute arthritis, especially in adults.4,5 The first reports of adverse pregnancy outcomes associated with parvovirus B19 infection were published in 1984, when parvovirus B19 infection was linked to cases of hydrops fetalis and fetal death.6,7.

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Authors
  1. John F. Rodis
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  2. Anthony M. Vintzileos
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Editors and Affiliations

  1. Department of Obstetrics and Gynecology, Wayne State University School of Medicine, 6071 West Outer Drive, 48235, Detroit, MI, USA

    Bernard Gonik M.D. (Professor and Vice Chairman Chief of Obstetrics and Gynecology—Grace Hospital) (Professor and Vice Chairman Chief of Obstetrics and Gynecology—Grace Hospital)

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Rodis, J.F., Vintzileos, A.M. (1994). Parvovirus. In: Gonik, B. (eds) Viral Diseases in Pregnancy. Clinical Perspectives in Obstetrics and Gynecology. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2640-6_11

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  • DOI: https://doi.org/10.1007/978-1-4612-2640-6_11

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