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Pituitary Control of Fetal and Adult Leydig Cells and Physiological Regulation of Gonadotropin Gene Expression and Secretion in the Male

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Function of Somatic Cells in the Testis

Part of the book series: Serono Symposia, USA ((SERONOSYMP))

Abstract

The cloning of genes for the gonadotropins has shifted the emphasis of physiological research on these hormones from their synthesis and secretion to the expression of the gonadotropin subunit mRNAs. These methodological advancements have undoubtedly broadened our view. In addition, important developments have taken place in the methods for gonadotropin measurement. These include the new supersensitive and specific immunoassays based on use of monoclonal antibodies and the immunometric assay principles (1, 2). The methods for measurement of gonadotropin bioactivity have also developed recently, especially as regards FSH (3–5). It is obvious that the molecular biological approaches, combined with the novel methods of gonadotropin measurement, will provide an improved arsenal for further elucidation of the physiology of gonadotropin synthesis, secretion, and actions.

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Authors
  1. I. Huhtaniemi
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  2. P. Pakarinen
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  3. M. Bergendahl
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  4. A. Perheentupa
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  5. T. Matikainen
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  6. A.-M. Haavisto
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Editors and Affiliations

  1. Department of Physiology School of Medicine, Southern Illinois University, Carbondale, IL, 62901-6512, USA

    Andrzej Bartke Ph.D.

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Huhtaniemi, I., Pakarinen, P., Bergendahl, M., Perheentupa, A., Matikainen, T., Haavisto, AM. (1994). Pituitary Control of Fetal and Adult Leydig Cells and Physiological Regulation of Gonadotropin Gene Expression and Secretion in the Male. In: Bartke, A. (eds) Function of Somatic Cells in the Testis. Serono Symposia, USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2638-3_12

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  • DOI: https://doi.org/10.1007/978-1-4612-2638-3_12

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7619-7

  • Online ISBN: 978-1-4612-2638-3

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