Lasers for Treatment of Occlusive Vascular Disease

  • Douglas Murphy-Chutorian
Conference paper
Part of the Contemporary Perspectives in Neurosurgery book series (COPENEU)


The object of this chapter is to present two approaches I have initiated that use laser energy to treat occlusive vascular disease: the Eclipse 2100 mid-infrared laser (Eclipse Surgical Technologies) and the SmartLaser (MCM Laboratories). The devices employ distinctly different strategies and technologies in laser therapy. Both are undergoing investigational trials in peripheral and coronary arteries with the hope of improving on the results of conventional therapies (i.e., balloon angioplasty and bypass surgery).


Laser Therapy Balloon Angioplasty YSGG Laser Laser Firing Laser Angioplasty 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Suggested Reading

  1. Aretz, HT, Butterly JR, Jewell ER, Setzer SE, Shapshay SM: Effects of holmium-YSGG laser irradiation on arterial tissue: preliminary results. SPIE 1989; 1067:127.Google Scholar
  2. Bartorelli AL, Almagor Y, Prevosti L, et al: In vivo coronary plaque recognition by fluorescence spectroscopy. Circulation 1988;78:11–294.Google Scholar
  3. Bartorelli AL, Bonner R, Almagor Y, et al: Enhanced recognition of plaque composition in vivo using laser excited fluorescence spectroscopy. J Am Coll Cardiol 1989; 13(2):54A.Google Scholar
  4. Geschwind H, Bonner F, Boussignac G, et al: Percutaneous pulsed laser angioplasty.Google Scholar
  5. in humans. J Am Coll Cardiol 1988;11:107A. Geschwind HJ, Dubois-Rande JL, Boussignac G: Early and long-term results after guided pulsed laser balloon angioplasty of totally occluded arteries. Circulation (in press, 1989).Google Scholar
  6. Geschwind HJ, Dubois-Rande JL, Poirot J, Boussignac G: Guided percutaneous pulsed laser angioplasty: results and follow-up. J Am Coll Cardiol 1989; 13(2): 13A.Google Scholar
  7. Geschwind HJ, Dubois-Rande JL, Shafton EP, et al: Circulation 1988;78:11–504.Google Scholar
  8. Geschwind H, Dubois-Rande JL, Shafton EP, et al: Pulsed laser-assisted balloon angioplasty guided by spectroscopy. Am Heart J 1989; 117:1147.PubMedCrossRefGoogle Scholar
  9. Leon MB, Almagor Y, Bartorelli A, et al: Fluorescence-guided laser angioplasty in patients with femoral popliteal occlusions Circulation 1988;78:11–294.Google Scholar
  10. Leon MB, Geschwind H, Selzer P, Bonner R: Fluorescence guided laser angioplasty Circulation (in press).Google Scholar
  11. Leon MB, Prevosti LG, Smith PD, et al: In vivo laser-induced fluorescence plaque detection: preliminary results in patients. Circulation 1987;76:IV–408.Google Scholar
  12. Leon MB, Lu D, Prevosti L, et al: Human arterial surface fluorescence: atherosclerotic plaque identification and effects of laser atheroma ablation. J Am Coll Cardiol 1988;12:94.PubMedCrossRefGoogle Scholar
  13. Leon MB, Prevosti L, Smith P, et al: Probe and fire angioplasty: fluorescence atheroma detection and selection laser atheroma ablation. Circulation 1987;76:IV–409.Google Scholar
  14. Murphy-Chutorian D, Selzer P, Kosek J, et al: The interaction between excimer laser energy and vascular tissue. Am Heart J 1986;112:739.PubMedCrossRefGoogle Scholar
  15. Murphy-Chutorian D, Selzer P, Wexler L, et al: Cardiovascular laser research at Stanford University. Semin Intervent Radiol 1986;3:61.CrossRefGoogle Scholar
  16. Moore W, Ahn S (eds): Endovascular Surgery. Philadelphia: Saunders, 1989.Google Scholar
  17. Nuss RC, Fabian RL, Sarkar R, Puliafito CA: Infrared laser bone ablation. Lasers Surg Med 1988;8:381.PubMedCrossRefGoogle Scholar
  18. Oz MC, Bass LS, Popp HW et al: In vitro comparison of thulium-holmium-chro-mium: YAG and argon ion lasers for welding of biliary tissue. Lasers Surg Med 1989;9:248.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag New York, Inc. 1995

Authors and Affiliations

  • Douglas Murphy-Chutorian

There are no affiliations available

Personalised recommendations