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Bovine Spongiform Encephalopathy pp 325–337Cite as

Elimination of Scrapie-Agent Infectivity in Naturally Derived Biologics

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Abstract

It is now almost 10 years since bovine spongiform encephalopathy (BSE) was first recognized, and considerable effort has been made to answer questions raised by its unexpected and undesirable appearance (1, 2). Epidemiologic studies have confirmed that BSE on a large-scale is found exclusively in adult cattle of the United Kingdom, while rare cases have been confirmed in indigenous cattle of very few other European nations. The disease has also appeared sporadically in cattle exported from the United Kingdom to other countries in Europe and elsewhere. The probable cause of the outbreak in the United Kingdom has been associated with significant changes in the manufacturing procedures used to prepare the meat and bone meal subsequently fed to cattle (3).

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Authors
  1. Alessandro Di Martino
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Editors and Affiliations

  1. Laboratory of Central Nervous System Studies Basic Neurosciences Program Division of Intramural Research, National Institute of Neurological Disorders and Stroke National Institutes of Health, Bethesda, MD, 20892-4122, USA

    Clarence J. Gibbs Jr. Ph.D.

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© 1996 Springer-Verlag New York, Inc.

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Di Martino, A. (1996). Elimination of Scrapie-Agent Infectivity in Naturally Derived Biologics. In: Gibbs, C.J. (eds) Bovine Spongiform Encephalopathy. Serono Symposia USA Norwell, Massachusetts. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2406-8_24

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  • DOI: https://doi.org/10.1007/978-1-4612-2406-8_24

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7527-5

  • Online ISBN: 978-1-4612-2406-8

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