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31P-MRS of Muscle Physiology

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Muscle Imaging in Health and Disease

Abstract

The primary function of skeletal muscle is to convert the chemical energy in food to the kinetic energy of motion. Without a properly functioning skeletal muscle system, we could not perform most of the activities necessary to sustain life. In performing this basic function, skeletal muscle exhibits its most distinctive characteristic: a large metabolic dynamic range. Unlike most tissues in the body, the metabolic rate of resting skeletal muscle is very low. During exercise, however, its metabolic rate increases greatly, and during peak exercise it can be almost two orders of magnitude greater than it is during rest. This differentiates skeletal muscle from all the other tissues of the body and makes it an attractive subject of study by 31P magnetic resonance spectroscopy (31P-MRS). This chapter will focus on two of the most commonly used applications of 31P-MRS: (1) monitoring energy metabolism during the transition from rest to exercise and (2) using these measurements to understand the underlying biochemistry and physiology of skeletal muscle in vivo.

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Authors
  1. Loren A. Bertocci
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Editors and Affiliations

  1. Department of Radiology, University of Texas Southwestern Medical Center at Dallas, 75235-9071, Dallas, TX, USA

    James L. Fleckenstein MD

  2. RadNet, Inc, 90025-3303, Los Angeles, CA, USA

    John V. Crues III MD

  3. Abteilung für Klinische Neurophysiologie, Universität Göttingen, 37075, Göttingen, Germany

    Carl D. Reimers MD

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© 1996 Springer-Verlag New York, Inc.

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Bertocci, L.A. (1996). 31P-MRS of Muscle Physiology. In: Fleckenstein, J.L., Crues, J.V., Reimers, C.D. (eds) Muscle Imaging in Health and Disease. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2314-6_9

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  • DOI: https://doi.org/10.1007/978-1-4612-2314-6_9

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7498-8

  • Online ISBN: 978-1-4612-2314-6

  • eBook Packages: Springer Book Archive

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