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Changes in Oocyte Number with Age: Effect on Fecundability

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Perimenopause

Part of the book series: Serono Symposia USA ((SERONOSYMP))

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Abstract

The oocyte reservoir in women is completed during fetal life during which time its progressive depletion starts and continues until a few years after menopause. Following the age of 30, this decrease in the oocyte reservoir is accompanied by a decrease in fertility potential (1). Although still a debatable issue, it is clear that this age-related reduction in fecundity is primarily due to oocyte aging rather than that of the uterus, because the implantation rate in older women, particularly women over 40, is tremendously improved and is equal to that of younger women when donated oocytes from younger women are used (2).

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Authors
  1. George B. Maroulis
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Editors and Affiliations

  1. Department of Obstetrics and Gynecology College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA

    Rogerio A. Lobo M.D.

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© 1997 Springer-Verlag New York, Inc.

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Maroulis, G.B. (1997). Changes in Oocyte Number with Age: Effect on Fecundability. In: Lobo, R.A. (eds) Perimenopause. Serono Symposia USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2288-0_3

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  • DOI: https://doi.org/10.1007/978-1-4612-2288-0_3

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7488-9

  • Online ISBN: 978-1-4612-2288-0

  • eBook Packages: Springer Book Archive

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