Cell Journeys: Even Germ Cells and Cells of the Peripheral Nervous System Originate from Emigrant Precursors
Animal embryos, especially those of vertebrates, are like cities full of tourists. In a translucent fish embryo migratory cells can be seen crawling and swarming (Fig. 3–38). In an avian and a mammalian blastodisc the cells of the meso “derm” do not form a “skin” (Greek: derma = skin) or a coherent germ “layer”; instead, the mesodermal cells creep around like amoebae to colonize the spaces between the epiblast and the hypoblast (Fig. 3–39, 3–48). When the somites split up, the cells of the sclerotome and the dermatome emigrate (Fig. 3–32, 9–5). Primordial germ cells, blood cells, and neural crest cells travel particularly long distances.
KeywordsMigration Transportation Germinal Epinephrine Tral
Bronner-Fraser, M. (1993): Environmental influences on neural crest cell migration. J. Neurobiol.
Bronner-Fraser, M., and Fraser, S.E. (1988): Cell lineage analysis reveals multipotency of some avian neural crest cells. Nature
335: 161–164.PubMedCrossRefGoogle Scholar
Collazo, A., Bronner-Fraser, M., and Fraser, S.E. (1993): Vital dye labelling of Xenopus laevis
trunk neural crest reveals multipotency and novel pathways of migration. Development
Eddy, E.M. (1975): Germ plasm and the differentiation of the germ line. Int. Rev. Cytol.
Erickson, C.A., and Goins, T.L. (1995): Avian neural crest cells can migrate in the dorsolateral path if they are specified as melanocytes. Development
Groves, A.K., and Anderson, D.J. (1996): Role of environmental signals and transcriptional regulators in neural crest development. Dev. Genet.
18: 64–72.PubMedCrossRefGoogle Scholar
Perris, R., von Boxburg, A., and Löfberg, J. (1988): Local embryonic matrices determine region-specific phenotypes in neural crest cells. Science
Richardson, M.K., and Sieber-Blum, M. (1993): Pluripotent neural crest cells in the developing skin of the quail embryo. Dev. Biol.
© Springer-Verlag New York, Inc. 1997