Skip to main content

Intraoperative Blood Salvage

  • Chapter

Abstract

Intraoperative blood salvage is an essential component of blood conservation efforts in cardiac surgery. Traditionally, cardiac surgical procedures necessitated the administration of large volumes of homologous blood products.1 The development of effective salvage techniques along with the introduction of nonblood priming solutions for the bypass circuit have played a major role in reducing and frequently eliminating the need for perioperative transfusion. Autotransfusion has been employed in a variety of noncardiac settings, such as vascular, trauma, and orthopedic surgery. However, the most extensive experience and the greatest benefits have been achieved in the field of cardiopulmonary bypass surgery. Several options exist for the processing of both intraoperative losses and residual bypass circuit blood. Each is associated with distinct advantages and disadvantages. The optimization of intraoperative blood salvage strategies may require a degree of flexibility, with specific techniques selected on an individual basis. This chapter reviews the major types of available salvage systems and discusses their benefits and limitations. In addition, we describe an approach that has worked well in our institution’s comprehensive blood conservation program.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Roche JK, Stengle JM. Open-heart surgery and the demand for blood.JAMA 1973;225:1516–1521.

    Article  PubMed  CAS  Google Scholar 

  2. Blundell J. Experiments on the transfusion of blood by the syringe.Med Chir Trans 1818;9:56–92.

    PubMed  CAS  Google Scholar 

  3. Highmore W. Practical remarks on an overlooked source of blood supply.Lancet 1874;1:89.

    Article  Google Scholar 

  4. Watson CM, Watson JR. Autotransfusion—review of American literature with report of two additional cases.Am J Surg 1936;33:232–237.

    Article  Google Scholar 

  5. Dyer RH. Intraoperative autotransfusion: a preliminary report and new method.Am J Surg 1966;112:874–878.

    Article  PubMed  Google Scholar 

  6. Klebanoff G. Early clinical experience with a disposable unit for the intraoperative salvage and reinfusion of blood loss (intraoperative autotransfusion).Am J Surg 1970;120:718–722.

    PubMed  CAS  Google Scholar 

  7. Housman LB. Hemofiltration, dialysis, and salvage techniques. In: Utley J, ed.Pathophysiology of Cardiopulmonary Bypass. Baltimore: Williams & Wilkins: 1993;113–123.

    Google Scholar 

  8. Duncan SE, Klebanoff G, Rogers W. A clinical experience with intraoperative autotransfusion.Ann Surg 1974;180:296–304

    Article  PubMed  CAS  Google Scholar 

  9. Duncan SE, Edwards WH, Dale WA. Caution regarding autotransfusion.Surgery 1974;76:1024–1029.

    PubMed  CAS  Google Scholar 

  10. Bretton P, Reines HD, Sade RM. Air embolization during autotransfusion for abdominal trauma.J Trauma 1985;25:165–166.

    Article  PubMed  CAS  Google Scholar 

  11. Thurer RL, Hauer J. Autotransfusion and blood conservation.Curr Probl Surg 1982;19:98–156.

    Article  Google Scholar 

  12. Williamson KR, Taswell HF. Intraoperative blood salvage: a review.Transfusion 1991;31:662–675.

    Article  PubMed  CAS  Google Scholar 

  13. Noon GP, Solis RT, Natelson EA, et al. A simple method of intraoperative autotransfusion.Surg Gynecol Obstet 1976;143:65–70.

    PubMed  CAS  Google Scholar 

  14. Clifford PC, Kruger AR, Smith A, et al. Salvage autotransfusion in aortic surgery: initial studies using a disposable reservoir.Br J Surg 1987;74:755–757.

    Article  PubMed  CAS  Google Scholar 

  15. Schaff HV, Hauer JM, Bell WR, et al. Retransfusion of shed mediastinal blood following cardiac surgery: a prospective study.J Thorac Cardiovasc Surv 1978;75:4–12.

    Google Scholar 

  16. Cosgrove DM, Thurer RL, Lytle BW, et al. Blood conservation during myocardial revascularization.Ann Thorac Surg 1979;28:184–188.

    Article  PubMed  CAS  Google Scholar 

  17. Breyer RH, Engelman RM, Rousou JA, et al. Blood conservation for myocardial revascularization. Is it cost effective?J Thorac Cardiovasc Surg 1987;93:512–522.

    PubMed  CAS  Google Scholar 

  18. Umlas J, O’Neill TP. Heparin removal in an autotransfuser device.Transfusion 1981;21:70–73.

    Article  PubMed  CAS  Google Scholar 

  19. Gravlee GP, Hopkins MB, Yetter CR, et al. Heparin content of washed red blood cells from the cardiopulmonary bypass circuit.J Cardiovasc Anesth 1992;6:140–142.

    CAS  Google Scholar 

  20. Haemonetics Cell Saver 4 Owner’s Operating Maintenance Manual. Massachusetts: Haemonetics Corporation, 1987.

    Google Scholar 

  21. Silverstein ME, Ford CA, Lysaght MJ, et al. Treatment of severe fluid overload by ultrafiltration.N Engl J Med 1974;291:747–751.

    Article  PubMed  CAS  Google Scholar 

  22. Klineberg PL, Kam CA, Johnson DC, et al. Hematocrit and blood volume control during cardiopulmonary bypass with use of hemofiltration.Anesthesiology 1984;60:478–480.

    Article  PubMed  CAS  Google Scholar 

  23. Magilligan DJ, Oyama C. Ultrafiltration during cardiopulmonary bypass: laboratory evaluation and initial clinical experience.Ann Thorac Surg 1984;37:33–39.

    Article  PubMed  Google Scholar 

  24. Hakim M, Wheeldon WD, Bethune DW, et al. Haemodialysis and haemofiltration on cardiopulmonary bypass.Thorax 1985;40:101–106.

    Article  PubMed  CAS  Google Scholar 

  25. Magilligan DJ. Indications for ultrafiltration in the cardiac surgical patient.J Thorac Cardiovasc Surg 1985;89:183–189.

    PubMed  Google Scholar 

  26. Boldt J, Zickmann B, Fedderson B, et al. Six different devices for blood conservation in cardiac surgery.Ann Thorac Surg 1991;51:747–753.

    Article  PubMed  CAS  Google Scholar 

  27. Page PA. Ultrafiltration versus cell washing for blood concentration.J Extra-corp Tech 1990;22:142–150.

    CAS  Google Scholar 

  28. Tamari Y, Nelson R, Hall M, et al. Conversion of dilute whole blood by single pass ultrafiltration.J Extracorp Tech 1983;15:126–131.

    Google Scholar 

  29. Cordell AR, Lavender SW. An appraisal of blood salvage techniques in vascular and cardiac operations.Ann Thorac Surg 1981;31:421–425.

    Article  PubMed  CAS  Google Scholar 

  30. Keeling MM, Gray LA, Brink MA, et al. Intraoperative autotransfusion. Experience in 725 consecutive cases.Ann Surg 1983;197:536–540

    Article  PubMed  CAS  Google Scholar 

  31. McCarthy PM, Popovsky MA, Schaff HV, et al. Effect of blood conservation efforts in cardiac operations at the Mayo Clinic.Mayo Clin Proc 1988;63:225–229.

    PubMed  CAS  Google Scholar 

  32. Mayer ED, Welsch M, Tanzeem A, et al. Reduction of postoperative donor blood requirement by use of the cell separator.Scand J Thorac Cardiovasc Surg 1985;19:165–171.

    PubMed  CAS  Google Scholar 

  33. Parrot D, Lancon JP, Merle JP, et al. Blood salvage in cardiac surgery.J Cardiothorac Vase Anesth 1991;5:454–456.

    Article  CAS  Google Scholar 

  34. Moran JM, Babka R, Silberman S, et al. Immediate centrifugation of oxygenator contents after cardiopulmonary bypass.J Thorac Cardiovasc Surg 1978;76:510–517.

    PubMed  CAS  Google Scholar 

  35. Winton TL, Charrette EJP, Salerno TA. The cell saver during cardiac surgery: Does it save?Ann Thorac Surg 1982;33:379–381.

    Article  PubMed  CAS  Google Scholar 

  36. Rosengart TK, Helm RE, Klemperer J, et al. Combined aprotinin and erythropoietin use for blood conservation: results with Jehovah’s Witnesses.Ann Thorac Surg 1994;58:1397–1403.

    Article  PubMed  CAS  Google Scholar 

  37. Giordano GF, Goldman DS, Mammana RB, et al. Intraoperative autotransfusion in cardiac operations. Effect on intraoperative and postoperative transfusion requirements.J Thorac Cardiovasc Surg 1988;96:382–386.

    PubMed  CAS  Google Scholar 

  38. Sutton RG, Kratz JM, Spinale FG, et al. Comparison of three blood-processing techniques during and after cardiopulmonary bypass. Ann Thorac Surg 1993;56:938–943.

    Article  PubMed  CAS  Google Scholar 

  39. Yaw PB, Sentany M, Link WJ, et al. Tumor cells carried through autotransfusion: contraindication to intraoperative blood recovery?JAMA 1975;231:490–491.

    Article  PubMed  CAS  Google Scholar 

  40. Homann B, Zenner HP, Schauber J, et al. Tumor cells carried through autotransfusion: are these cells still malignant?Acta Anaesthesiol Belg 1984;35(suppl):51–59.

    PubMed  Google Scholar 

  41. Hart OJ, Klimberg IW, Wasjman Z, et al. Intraoperative auto transfusion in radical cystectomy for carcinoma of the bladder.Surg Gynecol Obstet 1989;165:302–306.

    Google Scholar 

  42. Boudreaux JP, Bornside GH, Cohn I. Emergency autotransfusion: partial cleansing of bacterial-laden blood by cell washing.J Trauma 1983;23:31–35.

    Article  PubMed  CAS  Google Scholar 

  43. Timberlake GA, McSwain NE. Autotransfusion of blood contaminated by enteric contents: a potentially life-saving measure in the massively hemorrhaging trauma patient?J Trauma 1988;28:855–857.

    Article  PubMed  CAS  Google Scholar 

  44. Kluge RM, Calia RM, McLaughlin JS, et al. Sources of contamination in open heart surgery.JAMA 1974;230:1415–1418.

    Article  PubMed  CAS  Google Scholar 

  45. Schweiger IM, Gallagher CJ, Finlayson DC, et al. Incidence of cell-saver contamination during cardiopulmonary bypass.Ann Thorac Surg 1989;48:51–53.

    Article  Google Scholar 

  46. Bland LA, Villarino ME, Arduino MJ, et al. Bacteriologic and endotoxin analysis of salvaged blood used in autologous transfusions during cardiac operations.J Thorac Cardiovasc Surg 1992;103:582–588.

    PubMed  CAS  Google Scholar 

  47. Robicseck F, Duncan GD, Dorn GVR, et al. Inherent dangers of simultaneous application of microfibrillar collagen hemostat and blood-saving devices.J Thorac Cardiovasc Surg 1986;92:766–770.

    Google Scholar 

  48. Guidelines for blood salvage and reinfusion in surgery and trauma. American Association of Blood Banks, 1993.

    Google Scholar 

  49. Clifford PC, Kruger AR, Smith A, et al. Salvage autotransfusion in aortic surgery: initial studies using a disposable reservoir.Br J Surg 1987;74:755–757.

    Article  PubMed  CAS  Google Scholar 

  50. Ansell J, Parilla N, King M, et al. Survival of autotransfused red blood cells recovered from the surgical field during cardiovascular operations.J Thorac Cardiovasc Surg 1982;84:387–391.

    PubMed  CAS  Google Scholar 

  51. McShane AJ, Power C, Jackson JF, et al. Autotransfusion: quality of blood prepared with a red cell processing device.Br J Anaesth 1987;59:1035–1039.

    Article  PubMed  CAS  Google Scholar 

  52. Sharp WV, Stark M, Donovan DL. Modern autotransfusion. Experience with a washed red cell processing technique.Am J Surg 1981;142:522–524.

    Article  PubMed  CAS  Google Scholar 

  53. Ottesen S, Froysaker T. Use of Haemonetics Cell Saver for autotransfusion in cardiovascular surgery.Scand J Thor Cardiovasc Surg 1982;16:263–268.

    CAS  Google Scholar 

  54. Nakamura Y, Masada M, Toshima Y, et al. Comparative study of Cell Saver and ultrafiltration nontransfusion in cardiac surgery.Ann Thorac Surg 1990;49:973–978.

    Article  PubMed  CAS  Google Scholar 

  55. Tamari Y, Nelson R, Levy R, et al. Concentration of blood in the extracorporeal circuit using ultrafiltration.J Extracorp Tech 1983;15:133–142.

    Google Scholar 

  56. Boldt J, Kling D, von Bormann B, et al. Blood conservation in cardiac operations. Cell separation versus hemofiltration.J Thorac Cardiovasc Surg 1989;97:832–840.

    PubMed  CAS  Google Scholar 

  57. Breyer RH, Engelman RM, Rousou JA, et al. A comparison of Cell Saver versus ultrafilter during coronary artery bypass operations.J Thorac Cardiovasc Surg 1985;90:736–740.

    PubMed  CAS  Google Scholar 

  58. Johnson HD, Morgan MS, Utley JR, et al. Comparative analysis of recovery of cardiopulmonary bypass residual blood: Cell Saver versus hemoconcentrator.J Extracorp Tech 1994;26:194–199.

    CAS  Google Scholar 

  59. Solomon MD, Rutledge ML, Kane LE, et al. Cost comparison of intraoperative autologous versus homologous transfusion.Transfusion 1988;28:379–382.

    Article  PubMed  CAS  Google Scholar 

  60. Popovsky M, Devine PA, Taswell HF. Intraoperative autologous transfusion.Mayo Clin Proc 1985;60:125–134.

    PubMed  CAS  Google Scholar 

  61. Dekkers RJ, Rizzo RJ, Body SC, et al. Shed whole blood autotransfusion during aortic aneurysm operation with a modified collection infusion system.Ann Thorac Surg 1995;59:184–186.

    Article  PubMed  CAS  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer-Verlag New York, Inc.

About this chapter

Cite this chapter

Klemperer, J.D., Isom, O.W. (1998). Intraoperative Blood Salvage. In: Krieger, K.H., Isom, O.W. (eds) Blood Conservation in Cardiac Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2180-7_13

Download citation

  • DOI: https://doi.org/10.1007/978-1-4612-2180-7_13

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-0-387-94908-6

  • Online ISBN: 978-1-4612-2180-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics