Abstract
Conventional cardiac surgery performed in medical centers throughout the world would be impossible without the use of cardiopulmonary bypass. This technology diverts a patient’s circulating blood volume as it enters the right atrium and effectively supplants the functions of both the heart and lungs. During this process, blood is exposed to thrombogenic surfaces in the oxygenator and pump tubing before returning to the patient. A safe and reliable method of anticoagulation followed by reversal of anticoagulation is, therefore, crucial to the performance of cardiopulmonary bypass and the completion of complex cardiac surgical procedures. Presently, the most effective means of providing temporary anticoagulation is with heparin.
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© 1998 Springer-Verlag New York, Inc.
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Lahey, S.J. (1998). Monitoring of Coagulation: Management of Heparin and Protamine. In: Krieger, K.H., Isom, O.W. (eds) Blood Conservation in Cardiac Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2180-7_10
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DOI: https://doi.org/10.1007/978-1-4612-2180-7_10
Publisher Name: Springer, New York, NY
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