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Breast Conservation after Tumor Downstaging with Induction Chemotherapy

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Book cover Breast Cancer

Part of the book series: M.D. Anderson Solid Tumor Oncology Series ((MDA))

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Abstract

Breast conservation is a proved safe alternative to modified radical mastectomy for treatment of patients with early-stage breast cancer. Several large randomized trials have demonstrated that segmental mastectomy with axillary lymph node dissection and breast irradiation equals mastectomy in terms of overall and disease-free survival of patients with early-stage breast cancer. In addition to patient motivation for breast preservation, several criteria have emerged that are used to select appropriate candidates for breast-conserving procedures. It is generally recommended that patients with solitary lesions 4 cm or less in size with no skin or chest wall involvement and no specific contraindications for radiation therapy be considered candidates for breast-conserving therapy. Patients with tumors that fall outside these boundaries or who have a small breast size in relation to the size of the primary tumor are usually treated with mastectomy.

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Authors
  1. Kelly K. Hunt
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  2. Aman U. Buzdar
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Editor information

Editors and Affiliations

  1. Surgical Breast Section, Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Box 106, 1515 Holcombe Boulevard, Houston, TX, 77030, USA

    S. Eva Singletary M.D., FACS (Professor of Surgery, Chief) (Professor of Surgery, Chief)

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© 1999 Springer-Verlag New York, Inc.

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Hunt, K.K., Buzdar, A.U. (1999). Breast Conservation after Tumor Downstaging with Induction Chemotherapy. In: Singletary, S.E. (eds) Breast Cancer. M.D. Anderson Solid Tumor Oncology Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2146-3_14

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  • DOI: https://doi.org/10.1007/978-1-4612-2146-3_14

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7432-2

  • Online ISBN: 978-1-4612-2146-3

  • eBook Packages: Springer Book Archive

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