Abstract
Breast cancer is the most common cancer in women in the United States, and the mainstay of treatment for breast cancer is surgical resection. The type and extent of resection have changed dramatically over the last 40 years, with radical resections, popular during the 1950s and 1960s, being replaced by a more conservative approach as better understanding of the systemic nature of breast cancer has evolved. Regardless of whether a breast-conserving procedure or mastectomy is undertaken, dissection of the axillary nodes is a standard part of surgical therapy.
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Fisher B, Wolmark N, Bauer M, et al. The accuracy of clinical nodal staging and of limited axillary lymph node dissection as a determinant of histologic nodal status in carcinoma of the breast. Surg Gynecol Obstet 1981;152:765–771.
Haagensen C. Clinical classification and choice of treatment. In: Haagensen C (ed) Diseases of the Breast, 3rd ed. Philadelphia: Saunders, 1986;617–668.
March DE, Wechsler RJ, Kurtz AB, et al. CT-pathologic correlation of axillary lymph nodes in breast cancer. J Comput Assist Tomogr 1991;15:440–444.
Nieweg O, Kim E, Wong W, et al. Positron emission with fluoro 18-deoxyglucose in the detection and staging of breast cancer. Cancer 1993;71:3920–3925.
Avril N, Dose J, Janicke F, et al. Assessment of axillary lymph node involvement in breast cancer patients with positron emission tomography using radiolabeled 2-(fluorine-18)-fluoro-2-deoxy-D-glucose. J Natl Cancer Inst 1996;88:1204–1209.
Rosen PP, Lesser ML, Kinne DW, et al. Discontinuous or “skip” metastases in breast carcinoma: analysis of 1228 axillary lymph node dissections. Ann Surg 1983;197:276–283.
Veronesi U, Rilke F, Luini A, et al. Distribution of axillary node metastases by level of invasion. Cancer 1987;59:682–687.
Danforth DN Jr, Findlay PA, McDonald HD, et al. Complete axillary lymph node dissection for stage I—II carcinoma of the breast. J Clin Oncol 1985;4:655–662.
Pigott J, Nicholas R, Maddox WA, et al. Metastases to the upper levels of the axillary nodes in carcinoma of the breast and its implications for nodal sampling procedures. Surg Gynecol Obstet 1984;158:255–259.
National Institutes of Health Consensus Conference: treatment of early stage breast cancer. JAMA 1991;265:391–395.
Kissin MW, Thompson EM, Price AB, et al. The inadequacy of axillary sampling in breast cancer. Lancet 1982;1:1210–1212.
Steele RJ, Forrest AP, Gibson T, et al. The efficacy of lower axillary sampling in obtaining lymph node status in breast cancer: a controlled randomized trial. Br J Surg 1985;72:368–369.
Graversen HP, Blichert-Toft M, Andersen JA, et al. Breast cancer: risk of axillary recurrence in node-negative patients following partial dissection of the axilla. Eur J Surg Oncol 1988;14:407–412.
Fisher B, Redmond C, Fisher ER, et al. Ten year results of a randomized clinical trial comparing radical mastectomy and total mastectomy with and without radiation. N Engl J Med 1985;312:674–681.
Osborne MP, Ormiston N, Harmer CL, et al. Breast conservation in the treatment of early breast cancer: a 20 year follow-up. Cancer 1984;53:349–355.
Axelsson CK, Mouridsen HT, Zedeler K. Axillary lymph node dissection of level I and II lymph nodes is important in breast cancer classification: the Danish Breast Cancer Cooperative Group (DBCG). Eur J Cancer 1992;8A:1415–1418.
Lythgoe JP, Pamer MK. Manchester regional breast study: five and 10 year results. Br J Surg 1982;69:693–696.
Recht A, Pierce SM, Abner A, et al. Regional nodal failure after conservative surgery and radiotherapy for early stage breast carcinoma. J Clin Oncol 1991;9:988–996.
Fowble B, Solin LJ, Schultz DJ, et al. Frequency, sites of relapse and outcome of regional node failures following conservative surgery and radiation for early breast cancer. Int J Radiat Oncol Biol Phys 1989;17:703–710.
Haffty BG, Fischer D, Fischer JJ. Regional nodal irradiation in the conservative treatment of breast cancer. Int J Radiat Oncol Biol Phys 1990;19:859–865.
Cabanes PA, Salmon RJ, Vilcoq JR, et al. Value of axillary lymph node dissection in addition to lumpectomy and radiotherapy in early breast cancer. Lancet 1992:339:1245–1248.
Ivens D, Hoe AL, Podd CR, et al. Assessment of morbidity from complete axillary lymph node dissection. Br J Cancer 1991;66:136–138.
Werner R, McCormick B, Petrek J, et al. Arm edema in conservatively managed breast cancer: obesity is a major predictive factor. Radiology 1991;180:177–184.
Ryttov N, Holm NV, Quist N, et al. Influence of adjuvant irradiation on the development of late arm edema and impaired shoulder mobility after mastectomy for carcinoma of the breast. Acta Oncol 1988;27:667–670.
Lin PP, Allison DC, Wainstock J, et al. Impact of axillary lymph node dissection on the therapy of breast cancer patients. J Clin Oncol 1993;11:1636–1644.
Hladiuk M, Huuchroft S, Temple W, et al. Arm function after axillary lymph node dissection for breast cancer: a pilot study to provide parameter estimates. J Surg Oncol 1992;50:47–52.
Pezner R, Patterson M, Hill L. Arm edema in patients treated conservatively for breast cancer: relationship to patient age and axillary node dissection technique. Int J Radiat Oncol 1986;12:2079–2083.
Aitken D, Minton J. Complications associated with mastectomy. Surg Clin North Am 1983;63:1331–1352.
Wood K. Intercostobrachial nerve entrapment syndrome. South Med J 1978;71:662–663.
Siegel B, Mayzel K, Love S. Level I and level II axillary lymph node dissection in the treatment of early stage breast cancer. Arch Surg 1990;125:1144–1149.
Somers R, Jablon L, Kaplan M, et al. The use of closed suction drainage catheter after lumpectomy and axillary node dissection for breast cancer: a randomized trial. Ann Surg 1992;215:146–149.
Morrow M. Axillary node dissection: what role in managing breast cancer? Contemp Oncol 1994;8:16–27.
Wilson RE, Donegan WL, Mettlin C, et al. The 1982 national survey of carcinoma of the breast in the United States by the American College of Surgeons. Surg Gynecol Obstet 1984;159:309–318.
Carter CL, Allen C, Henson DE. Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases. Cancer 1989;63:181–187.
Winchester DJ, Menck HR, Fremgen AM, et al. Selection criteria for axillary lymph node dissection in breast cancer. Presented at the 48th Cancer Symposium of the Society for Surgical Oncology, Houston, March 1994.
Silverstein MJ, Gierson ED, Waisman JR, et al. Axillary lymph node dissection for T1a breast carcinomas: is it indicated? Cancer 1994;73:664–667.
Winchester DJ, Menck HR, Bland K, et al. Axillary lymph node metastases in an audit analysis of T1a breast cancers. Presented at the 50th Cancer Symposium of the Society of Surgical Oncology, Chicago, March 1997.
Silverstein MJ, Waisman JR, Gierson ED, et al. Can axillary lymph node dissection be eliminated for selected patients with invasive breast cancer by using a combination of tumor size and palpability to predict nodal positivity? Proc Am Soc Clin Oncol 1994;13:56–61.
Walls J, Boggis CR, Wilson M, et al. Treatment of the axilla in patients with screen-detected breast cancer. Br J Surg 1993;80:436–438.
Harris JR, Morrow M. Local management of invasive breast cancer. In: Harris JR, Lippman ME, Morrow M, Hellman S (eds) Diseases of the Breast. Philadelphia: Lippincott-Raven, 1996;487–547.
Wilhelm MC, Edge SB, Cole D, et al. Nonpalpable invasive breast cancer. Ann Surg 1992;213:600–605.
Chadha M, Chabon AB, Friedmann P, et al. Predictors of axillary lymph node metastases in patients with T1 breast cancer: a multivariate analysis. Cancer 1994;73:350–353.
Ravdin PM, DeLaurentis M, Vendely T, et al. Prediction of axillary lymph node status in breast cancer patients by use of prognostic indicators. J Natl Cancer Inst 1994;86:1771–1775.
Ashikari R, Huvos AG, Snyder RE. Prospective study of non-infiltrating carcinoma of the breast. Cancer 1977;39:435–439.
Westbrook KC, Gallager HS. Intraductal carcinoma of the breast: a comparative study. Am J Surg 1975;130:667–670.
Rosner D, Bedwani RN, Vana J, et al. Noninvasive breast carcinoma: results of a national survey by the American College of Surgeons. Ann Surg 1980;192:139–147.
Von Reuden DG, Wilson RE. Intraductal carcinoma of the breast. Surg Gynecol Obstet 1984;158:105–111.
Silverstein MJ, Waisman JR, Gamagami P, et al. Intraductal carcinoma of the breast (208) cases: clinical factors influencing treatment choice. Cancer 1990;66:102–108.
Solin LJ, Fowble BL, Schultz DJ, et al. Definitive irradiation for intraductal carcinoma of the breast. Int J Radiat Oncol Biol Phys 1990;19:843–850.
Fisher ER, Sass R, Risher B, et al. Pathologic findings from the National Surgical Adjuvant Breast Project (protocol 6), intraductal carcinoma (DCIS). Cancer 1986;57:197–208.
Brown PW, Silverman J, Owens E, et al. Intraductal “noninfiltrating” carcinoma of the breast. Arch Surg 1976;111:1063–1067.
Wong JH, Kopald KH, Morton DL. The impact of microinvasion on axillary node metastases and survival in patients with intraductal breast cancer. Arch Surg 1990;125:1298–1302.
Solin LJ, Fowble BL, Yeh IT, et al. Microinvasive ductal carcinoma of the breast treated with breast conserving surgery and definitive irradiation. Int J Radiat Oncol Biol Phys 1992;23:961–968.
Frazier TG, Copeland EM, Gallagher HS, et al. Prognosis and treatment in minimal breast cancer. Am J Surg 1977;133:697–701.
Nevin JE, Pinzon G, Moran TJ, et al. Minimal breast cancer. Am J Surg 1980;139:357–359.
Schuh ME, Nemoto T, Penetrante RB, et al. Intraductal carcinoma: analysis of presentation, pathologic findings and outcome of disease. Arch Surg 1986;121:1303–1307.
Kinne DW, Petrek JA, Osborne MP, et al. Breast carcinoma in situ. Arch Surg 1989; 124:333–336.
McDivitt RW, Boyce W, Gersell D. Tubular carcinoma of the breast: clinical and pathological observations concerning 135 cases. Am J Surg Pathol 1982;6:401–411.
Peters GN, Wolff M, Haagensen CD. Tubular carcinoma of the breast: clinical pathologic correlations based on 100 cases. Ann Surg 1981;193:138–149.
Systemic treatment of early breast cancer by hormonal cytotoxic, or immune therapy: Early Breast Cancer Trialist’s Collaborative Group. Lancet 1992;339:1–15.
Berlanger D, Moore M, Tannock I. How American oncologists treat breast cancer: an assessment of the influence of clinical trials. J Clin Oncol 1991;9:7–16.
Goldhirsh A, Wood WC, Senn HJ, et al. Meeting highlight: international consensus panel on treatment of primary breast cancer. J Natl Cancer Inst 1995;87:1441–1445.
Gelber RD, Cole BF, Goldhirsch A, et al. Adjuvant chemotherapy plus tamoxifen alone for postmenopausal breast cancer: meta-analysis of quality-adjusted survival. Lancet 1996;347:1066–1071.
Morton D, Wen DR, Wong J, et al. Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg 1992;127:392–399.
Giuliano AE, Kirgan DM, Guenther JM, et al. Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Ann Surg 1994;229:391–401.
Giuliano AE, Dale PS, Turner RR, et al. Improved axillary staging of breast cancer with sentinel lymphadenectomy. Ann Surg 1995;222:399–401.
Albertini JJ, Lyman GH, Cox C, et al. Lymphatic mapping and sentinel node biopsy in the patient with breast cancer. JAMA 1996;276:1818–1822.
Krag DN, Weaver DL, Alex JC, et al. Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe. Surg Oncol 1993;2:335–340.
Winchester DP, Menck HR, Osteen RT, et al. Treatment trends for ductal carcinoma in situ of the breast. Ann Surg Oncol 1995;2:207–213.
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Hansen, N., Morrow, M. (1999). Current Status of Axillary Node Dissection. In: Singletary, S.E. (eds) Breast Cancer. M.D. Anderson Solid Tumor Oncology Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2146-3_11
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DOI: https://doi.org/10.1007/978-1-4612-2146-3_11
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