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Body Composition Techniques for the Study of Osteoporosis

  • Conference paper
Quality of the Body Cell Mass

Part of the book series: Serono Symposia USA ((SERONOSYMP))

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Abstract

Until the widespread use of the dual energy X-ray absorptiometric (DXA) techniques, the ability to measure bone mass had been possible only in a few select centers worldwide. Studies in body composition related to osteoporosis and its treatment have been conducted at Brookhaven National Laboratory since the early 1970s by utilizing delayed gamma neutron activation analysis and the concurrent measurement of the induced gamma-emitting radioactivity in a whole-body counter (Aloia 1985a). The whole-body counter was upgraded in 1987 to use 32 NaI (Ti) detectors of 10×10×26 cm positioned in two arrays above and below the subjects (Cohn 1969). The activated isotope 49Ca decays with T½ of 8.72 minutes, emitting a characteristic 3.04 MeV gamma line, which is detected in the whole-body counter. The whole-body counter also measures total body potassium (TBK), which is a marker of fat-free mass (FFM). By subtraction of FFM from body weight, body fat mass can be calculated. Total body fat can also be measured directly, utilizing the inelastic neutron scatter technique described in Chapter 16.

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Authors
  1. Ashok N. Vaswani
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Editors and Affiliations

  1. Nutrition Research Center, St. Luke’-Roosevelt Hospital Center, New York, NY, 10025, USA

    Richard N. Pierson Jr. M.D.

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© 2000 Springer-Verlag New York, Inc.

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Vaswani, A.N. (2000). Body Composition Techniques for the Study of Osteoporosis. In: Pierson, R.N. (eds) Quality of the Body Cell Mass. Serono Symposia USA. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-2090-9_25

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  • DOI: https://doi.org/10.1007/978-1-4612-2090-9_25

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4612-7410-0

  • Online ISBN: 978-1-4612-2090-9

  • eBook Packages: Springer Book Archive

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