Cells are the fundamental units of living beings. Tissues, organs, and functional systems result from the assemblage of specialized cells interacting with each other. Studying cells outside their natural environment, i.e., isolated from their tissue and cell-type interactions, helps determine whether aging mechanisms also operate at the cellular level. Research has focused on how aging affects different types of cells and what intracellular modifications can be observed over time. The findings have profound implications for the theories of aging (Peacocke and Campisi, 1991).
KeywordsCystic Fibrosis Cellular Aging Familial Hypercholesterolemia Myotonic Dystrophy Triplet Repeat
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