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Apoptosis in the Ovary: The Role of DNase I

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Cell Death in Reproductive Physiology

Part of the book series: Proceedings in the Serono Symposia USA Series ((SERONOSYMP))

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Abstract

The essential function of the ovary, to produce oocytes and hormones, involves follicular development, ovulation, and luteinization. The predominant event in the ovary however, is the loss of follicles through atresia. Luteal regression depends on the reproductive state of the female and must occur before the next wave of follicular development can proceed. Follicular atresia and luteal regression account for the removal of most steroidogenic cells from the ovary, but the physiological mechanisms that underlie these two predominant and important aspects of ovarian function are not fully understood.

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Authors
  1. David L. Boone
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  2. Benjamin K. Tsang
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Editor information

Editors and Affiliations

  1. Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA, 02114, USA

    Jonathan L. Tilly Ph.D.

  2. Center for Research on Reproduction and Women’s Health, University of Pennsylvania School of Medicine, Philadelphia, PA, 19104, USA

    Jerome F. Strauss III M.D., Ph.D.

  3. W. Alton Jones Cell Science Center, Lake Placid, NY, 12946, USA

    Martin Tenniswood Ph.D.

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Boone, D.L., Tsang, B.K. (1997). Apoptosis in the Ovary: The Role of DNase I. In: Tilly, J.L., Strauss, J.F., Tenniswood, M. (eds) Cell Death in Reproductive Physiology. Proceedings in the Serono Symposia USA Series. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1944-6_19

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  • DOI: https://doi.org/10.1007/978-1-4612-1944-6_19

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