Abstract
The traditional outcomes of interest in clinical trials are survival, negative events (complications), failure of treatment, and recurrence of disease. 1 These endpoints are appropriate when the patient’s return to normal health and activity can be expected within a relatively short period of time. They have to be altered when we evaluate treatment options that aim to increase general health or overall quality of life. This is especially true when palliative care is applied. In these patients, a return to normal “health” and “activity” cannot be expected (Table 34-1).
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Paul, A., Bouillon, B. (1998). Developing a Measuring Instrument. In: Troidl, H., McKneally, M.F., Mulder, D.S., Wechsler, A.S., McPeek, B., Spitzer, W.O. (eds) Surgical Research. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1888-3_34
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