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Effect of Growth Hormone Administration on Colonic Healing and Repair

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Book cover Growth Factors and Wound Healing

Part of the book series: Serono Symposia USA Norwell, Massachusetts ((SERONOSYMP))

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Abstract

The understanding of anastomotic healing and wound management is fundamental in surgery because leakage of a colorectal anastomosis increases threefold the postoperative morbidity and remains the most important mortality factor in gastrointestinal surgery (1, 2). Rates of clinically manifest leaks of colonic anastomoses have been reported to reach 14%, and x-ray inspection of extraperitoneal anastomoses has revealed leakage rates of up to 51% (3, 4).

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Authors
  1. Henrik Christensen
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Editors and Affiliations

  1. Department of Medicine, Emory University School of Medicine, Atlanta, GA, 30322, USA

    Thomas R. Ziegler M.D.

  2. Department of Preclinical Development, PRIZM Pharmaceuticals, San Diego, CA, 92121, USA

    Glenn F. Pierce Ph.D., M.D.

  3. Shriners Burns Institute, The University of Texas Medical Branch, Galveston, TX, 77550, USA

    David N. Herndon M.D.

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Christensen, H. (1997). Effect of Growth Hormone Administration on Colonic Healing and Repair. In: Ziegler, T.R., Pierce, G.F., Herndon, D.N. (eds) Growth Factors and Wound Healing. Serono Symposia USA Norwell, Massachusetts. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-1876-0_15

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